| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | promethazine 11.2 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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58 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:I12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STAP2 | signal transducing adaptor family member 2 | 6.97767 |
| GPER1 | G protein-coupled estrogen receptor 1 | 4.66105 |
| KDM5D | lysine (K)-specific demethylase 5D | 4.3721 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 3.58658 |
| RIC8A | RIC8 guanine nucleotide exchange factor A | 3.39639 |
| KCTD5 | potassium channel tetramerization domain containing 5 | 3.27801 |
| SIRT3 | sirtuin 3 | 3.2194 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 3.0524 |
| AGR2 | anterior gradient 2 | 2.9674 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.7295 |
| MAMLD1 | mastermind-like domain containing 1 | 2.64002 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 2.57633 |
| TLCD3A | TLC domain containing 3A | 2.57555 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 2.56987 |
| DENND2D | DENN/MADD domain containing 2D | 2.54024 |
| HOXA10 | homeobox A10 | 2.43185 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 2.28495 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.25435 |
| PSMD13 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | 2.25403 |
| MELK | maternal embryonic leucine zipper kinase | 2.24311 |
| DEAF1 | DEAF1 transcription factor | 2.21115 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 2.16795 |
| RBM47 | RNA binding motif protein 47 | 2.15668 |
| CD151 | CD151 molecule (Raph blood group) | 2.12995 |
| MXRA7 | matrix-remodelling associated 7 | 2.1253 |
| TSC22D4 | TSC22 domain family, member 4 | 2.04898 |
| MICALL1 | MICAL-like 1 | 2.00202 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -5.3828 |
| TEX10 | testis expressed 10 | -5.07327 |
| RPIA | ribose 5-phosphate isomerase A | -4.98876 |
| CLTB | clathrin, light chain B | -4.30098 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | -3.23545 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | -2.82611 |
| LOC124905557 | eukaryotic translation initiation factor 1A, X-chromosomal | -2.79482 |
| TUBA4A | tubulin, alpha 4a | -2.71352 |
| KLK6 | kallikrein-related peptidase 6 | -2.71177 |
| KLK8 | kallikrein-related peptidase 8 | -2.58943 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | -2.51152 |
| KDM5C | lysine (K)-specific demethylase 5C | -2.49931 |
| SMC1A | structural maintenance of chromosomes 1A | -2.46883 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -2.43041 |
| KDM6A | lysine (K)-specific demethylase 6A | -2.40411 |
| SDC1 | syndecan 1 | -2.28384 |
| LCN2 | lipocalin 2 | -2.25682 |
| PUDP | pseudouridine 5'-phosphatase | -2.24205 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -2.23242 |
| OLFML3 | olfactomedin-like 3 | -2.22857 |
| FAM13B | family with sequence similarity 13, member B | -2.21265 |
| DEFA4 | defensin, alpha 4, corticostatin | -2.20279 |
| ZRSR2 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 | -2.19422 |
| PRR15L | proline rich 15-like | -2.13808 |
| CDA | cytidine deaminase | -2.11607 |
| TICAM1 | toll-like receptor adaptor molecule 1 | -2.1159 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | -2.11542 |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 | -2.07021 |
| IFI27 | interferon, alpha-inducible protein 27 | -2.06697 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -2.0144 |
| TAGLN3 | transgelin 3 | -2.0093 |
