CRCGN017_MCF10A.TP53.M_24H:I13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description trans-cinnamaldehyde 100.8 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:I13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PEX11A peroxisomal biogenesis factor 11 alpha 4.80467
WFS1 Wolfram syndrome 1 (wolframin) 4.69697
MAMLD1 mastermind-like domain containing 1 4.59968
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 4.50622
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 3.31753
CNRIP1 cannabinoid receptor interacting protein 1 3.19179
IGFBP3 insulin-like growth factor binding protein 3 2.67044
CCL2 chemokine (C-C motif) ligand 2 2.58322
NOSIP nitric oxide synthase interacting protein 2.47606
SAMHD1 SAM domain and HD domain 1 2.0536
PRKCQ protein kinase C, theta 2.0353

decreased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I -3.47676
GDF15 growth differentiation factor 15 -3.47251
DIPK1A divergent protein kinase domain 1A -2.82263
KIF14 kinesin family member 14 -2.69374
RNF167 ring finger protein 167 -2.67118
HTRA1 HtrA serine peptidase 1 -2.61859
HMG20B high mobility group 20B -2.28839
CBR1 carbonyl reductase 1 -2.05909
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -2.05593