CRCGN017_MCF10A.TP53.M_24H:I19 Gene Set
Genes
38 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:I19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.28087
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
4.21987
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
4.11196
|
|
AGR2
|
anterior gradient 2
|
3.74835
|
|
DNMT1
|
DNA (cytosine-5-)-methyltransferase 1
|
3.47653
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
2.95293
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.63671
|
|
RAB21
|
RAB21, member RAS oncogene family
|
2.57166
|
|
BAD
|
BCL2-associated agonist of cell death
|
2.54179
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.48876
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
2.4382
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
2.4204
|
|
IFT57
|
intraflagellar transport 57
|
2.35032
|
|
SAP30L
|
SAP30-like
|
2.29981
|
|
CTNNAL1
|
catenin (cadherin-associated protein), alpha-like 1
|
2.27383
|
|
CTBP2
|
C-terminal binding protein 2
|
2.1271
|
|
EVI2B
|
ecotropic viral integration site 2B
|
2.12661
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.12324
|
|
CAMK1
|
calcium/calmodulin-dependent protein kinase I
|
2.06745
|
|
LAMA5
|
laminin, alpha 5
|
2.03708
|
|
SMU1
|
smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
|
2.01213
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DIPK1A
|
divergent protein kinase domain 1A
|
-4.65745
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
-4.55768
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.55024
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-4.3891
|
|
ARPP19
|
cAMP-regulated phosphoprotein, 19kDa
|
-3.87187
|
|
PPIC
|
peptidylprolyl isomerase C (cyclophilin C)
|
-3.75484
|
|
ETFB
|
electron-transfer-flavoprotein, beta polypeptide
|
-2.88086
|
|
ESF1
|
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
|
-2.58776
|
|
SPRED2
|
sprouty-related, EVH1 domain containing 2
|
-2.4017
|
|
CPEB1
|
cytoplasmic polyadenylation element binding protein 1
|
-2.31799
|
|
ARHGEF2
|
Rho/Rac guanine nucleotide exchange factor (GEF) 2
|
-2.26708
|
|
PAM16
|
presequence translocase-associated motor 16 homolog (S. cerevisiae)
|
-2.1318
|
|
KCNE4
|
potassium channel, voltage gated subfamily E regulatory beta subunit 4
|
-2.12625
|
|
E2F6
|
E2F transcription factor 6
|
-2.10518
|
|
PDGFRB
|
platelet-derived growth factor receptor, beta polypeptide
|
-2.10201
|
|
RAI14
|
retinoic acid induced 14
|
-2.07214
|
|
CLIP3
|
CAP-GLY domain containing linker protein 3
|
-2.02564
|