CRCGN017_MCF10A.TP53.M_24H:I20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tributyl phosphate 33.32 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:I20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADGRE5 adhesion G protein-coupled receptor E5 5.2652
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 5.23028
PPARG peroxisome proliferator-activated receptor gamma 4.5718
WFS1 Wolfram syndrome 1 (wolframin) 4.556
OXSR1 oxidative stress responsive 1 3.76945
HLA-DRA major histocompatibility complex, class II, DR alpha 3.6649
GARRE1 granule associated Rac and RHOG effector 1 3.4443
GRB10 growth factor receptor-bound protein 10 3.35818
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.60755
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 2.59825
CETN3 centrin, EF-hand protein, 3 2.30885
TRAPPC4 trafficking protein particle complex 4 2.3081

decreased expression

Symbol Name Standardized Value
TARBP1 TAR (HIV-1) RNA binding protein 1 -5.4279
TM9SF3 transmembrane 9 superfamily member 3 -5.1618
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.89685
CHMP4B charged multivesicular body protein 4B -4.58527
CORO1A coronin, actin binding protein, 1A -3.38445
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -3.18432
BASP1 brain abundant, membrane attached signal protein 1 -3.17275
RPP38 ribonuclease P/MRP 38kDa subunit -2.1379
OAT ornithine aminotransferase -2.0093