CRCGN017_MCF10A.TP53.M_24H:I22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methyleugenol 101.98 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

30 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:I22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
METRN meteorin, glial cell differentiation regulator 4.36037
CNRIP1 cannabinoid receptor interacting protein 1 3.71586
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 3.62575
HBB hemoglobin, beta 2.99386
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.98704
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.09284
KDM5D lysine (K)-specific demethylase 5D 2.08361
HBA1 hemoglobin, alpha 1 2.02007
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 2.01367

decreased expression

Symbol Name Standardized Value
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -4.81281
HMG20B high mobility group 20B -4.14036
DNM1L dynamin 1-like -4.05961
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.75723
CAPRIN2 caprin family member 2 -3.63518
PSIP1 PC4 and SFRS1 interacting protein 1 -2.97704
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.93351
KRT14 keratin 14, type I -2.91485
NISCH nischarin -2.87415
GDF15 growth differentiation factor 15 -2.84167
COTL1 coactosin-like F-actin binding protein 1 -2.5908
MTERF3 mitochondrial transcription termination factor 3 -2.49101
DENR density-regulated protein -2.45477
MSN moesin -2.28935
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.23007
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.22263
RESF1 retroelement silencing factor 1 -2.17467
PIGG phosphatidylinositol glycan anchor biosynthesis, class G -2.1721
INTS13 integrator complex subunit 13 -2.13633
LOC124905557 eukaryotic translation initiation factor 1A, X-chromosomal -2.09006
ANXA2 annexin A2 -2.06334