CRCGN017_MCF10A.TP53.M_24H:I24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methyleugenol 11.33 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:I24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPP1R13B protein phosphatase 1, regulatory subunit 13B 4.32859
INTS3 integrator complex subunit 3 3.87958
CCDC92 coiled-coil domain containing 92 3.40015
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 3.01968
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.91922
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.79884
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.55618
HBB hemoglobin, beta 2.3591
CNRIP1 cannabinoid receptor interacting protein 1 2.27798
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.22228
ALOX15 arachidonate 15-lipoxygenase 2.10708
RFX5 regulatory factor X, 5 (influences HLA class II expression) 2.05306
MAMLD1 mastermind-like domain containing 1 2.01167

decreased expression

Symbol Name Standardized Value
NPDC1 neural proliferation, differentiation and control, 1 -7.00467
UFM1 ubiquitin-fold modifier 1 -4.28306
KIF14 kinesin family member 14 -3.8718
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -3.20422
PIH1D1 PIH1 domain containing 1 -2.95552
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.83133
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -2.74052
C2CD5 C2 calcium-dependent domain containing 5 -2.54053
ADI1 acireductone dioxygenase 1 -2.38395
CCDC86 coiled-coil domain containing 86 -2.28054
RAD51C RAD51 paralog C -2.01027