CRCGN017_MCF10A.TP53.M_24H:J03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-chloro-p-phenylenediamine sulfate 11.09 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:J03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.87816
ARID4B AT rich interactive domain 4B (RBP1-like) 2.17891
MRPL12 mitochondrial ribosomal protein L12 2.14611
TXNRD1 thioredoxin reductase 1 2.08979
ECSIT ECSIT signalling integrator 2.04349
PNKP polynucleotide kinase 3'-phosphatase 2.02345
RCC1L RCC1 like 2.01641

decreased expression

Symbol Name Standardized Value
CCDC86 coiled-coil domain containing 86 -5.06493
BASP1 brain abundant, membrane attached signal protein 1 -3.43293
THAP11 THAP domain containing 11 -2.82974
EBNA1BP2 EBNA1 binding protein 2 -2.37712
BCAT1 branched chain amino-acid transaminase 1, cytosolic -2.26761
TRAPPC3 trafficking protein particle complex 3 -2.22104
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -2.17593
YME1L1 YME1-like 1 ATPase -2.16817
RGS2 regulator of G-protein signaling 2 -2.16803
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.11454
TENT4A terminal nucleotidyltransferase 4A -2.04493
CANT1 calcium activated nucleotidase 1 -2.03155