CRCGN017_MCF10A.TP53.M_24H:J04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4-nitro-o-phenylenediamine 99.8 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

617 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:J04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HMOX1 heme oxygenase 1 10.0
NUCB2 nucleobindin 2 7.90475
TXNRD1 thioredoxin reductase 1 7.65922
ABHD4 abhydrolase domain containing 4 5.47624
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 4.85986
GLRX glutaredoxin (thioltransferase) 4.76954
UGDH UDP-glucose 6-dehydrogenase 4.61916
LRP10 low density lipoprotein receptor-related protein 10 4.39543
ABHD6 abhydrolase domain containing 6 4.36858
SQSTM1 sequestosome 1 4.17183
CNRIP1 cannabinoid receptor interacting protein 1 4.0686
MUC1 mucin 1, cell surface associated 3.96429
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 3.95271
AGO4 argonaute RISC catalytic component 4 3.84405
FOXO4 forkhead box O4 3.71394
RAP1GAP RAP1 GTPase activating protein 3.65657
CAPN1 calpain 1, (mu/I) large subunit 3.65053
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 3.64488
SMIM40 small integral membrane protein 40 3.52959
TRIM16 tripartite motif containing 16 3.52897
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.49465
MINDY1 MINDY lysine 48 deubiquitinase 1 3.32306
BCL2L13 BCL2-like 13 (apoptosis facilitator) 3.28992
SYNE2 spectrin repeat containing, nuclear envelope 2 3.28589
OXSR1 oxidative stress responsive 1 3.2683
WFS1 Wolfram syndrome 1 (wolframin) 3.18604
ADAM10 ADAM metallopeptidase domain 10 3.16579
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 3.13809
EAPP E2F-associated phosphoprotein 3.12299
BLVRB biliverdin reductase B 3.11467
CERK ceramide kinase 3.10586
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 3.08435
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 3.06172
GABARAPL1 GABA(A) receptor-associated protein like 1 3.04389
KLHL36 kelch-like family member 36 3.03761
GFPT1 glutamine--fructose-6-phosphate transaminase 1 3.02604
HSPB1 heat shock 27kDa protein 1 3.01908
LIN7A lin-7 homolog A (C. elegans) 3.00491
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 3.0029
RAB9A RAB9A, member RAS oncogene family 2.96663
DHRS7 dehydrogenase/reductase (SDR family) member 7 2.95963
VGLL4 vestigial-like family member 4 2.94703
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.92418
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 2.92368
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 2.90712
HBA1 hemoglobin, alpha 1 2.89299
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.88578
TMEM134 transmembrane protein 134 2.88118
HBB hemoglobin, beta 2.87835
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 2.85481
SLC35B1 solute carrier family 35, member B1 2.84874
CTSL cathepsin L 2.81748
IRAK4 interleukin-1 receptor-associated kinase 4 2.79938
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 2.79747
WASHC3 WASH complex subunit 3 2.78401
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 2.78021
TMEM59 transmembrane protein 59 2.77247
MSRB1 methionine sulfoxide reductase B1 2.75902
COQ10B coenzyme Q10 homolog B (S. cerevisiae) 2.74941
MYL5 myosin, light chain 5, regulatory 2.74093
KRCC1 lysine-rich coiled-coil 1 2.72123
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 2.7176
TSKU tsukushi, small leucine rich proteoglycan 2.71518
LLGL2 lethal giant larvae homolog 2 (Drosophila) 2.69391
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 2.68865
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2.66498
PIR pirin (iron-binding nuclear protein) 2.6643
KEAP1 kelch-like ECH-associated protein 1 2.6621
ZNF750 zinc finger protein 750 2.652
CRAT carnitine O-acetyltransferase 2.65173
FOSL2 FOS-like antigen 2 2.65109
RNF103 ring finger protein 103 2.6499
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.63856
TMEM106B transmembrane protein 106B 2.63788
WBP1L WW domain binding protein 1-like 2.62719
TM7SF2 transmembrane 7 superfamily member 2 2.62097
CES1 carboxylesterase 1 2.61753
ARID4B AT rich interactive domain 4B (RBP1-like) 2.61705
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 2.60816
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 2.60224
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 2.60062
HS1BP3 HCLS1 binding protein 3 2.59875
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 2.5954
CIRSR corepressor of RBPJ and splicing regulator 2.58916
LGMN legumain 2.57041
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 2.56598
CCDC90B coiled-coil domain containing 90B 2.56106
BATF basic leucine zipper transcription factor, ATF-like 2.55919
RAB4B RAB4B, member RAS oncogene family 2.5547
LOC114841035 uncharacterized LOC114841035 2.55151
WIF1 WNT inhibitory factor 1 2.54901
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 2.54585
CCDC92 coiled-coil domain containing 92 2.52091
MPPE1 metallophosphoesterase 1 2.51334
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 2.51216
KDM4A lysine (K)-specific demethylase 4A 2.50866
RNF122 ring finger protein 122 2.50476
NQO1 NAD(P)H dehydrogenase, quinone 1 2.49783
SERTAD3 SERTA domain containing 3 2.49721
APH1B APH1B gamma secretase subunit 2.49325
GATA3 GATA binding protein 3 2.48605
MYH9 myosin, heavy chain 9, non-muscle 2.4769
BAZ2B bromodomain adjacent to zinc finger domain, 2B 2.47565
OCEL1 occludin/ELL domain containing 1 2.47494
EPHX3 epoxide hydrolase 3 2.47463
TPD52L1 tumor protein D52-like 1 2.47341
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 2.47173
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 2.45053
CPT1A carnitine palmitoyltransferase 1A (liver) 2.44556
KLHL24 kelch-like family member 24 2.43298
YPEL5 yippee-like 5 (Drosophila) 2.43073
GLTP glycolipid transfer protein 2.41476
CKMT1A creatine kinase, mitochondrial 1A 2.41275
MSRA methionine sulfoxide reductase A 2.4093
EEIG1 estrogen-induced osteoclastogenesis regulator 1 2.40732
SPTSSA serine palmitoyltransferase, small subunit A 2.4063
GSTZ1 glutathione S-transferase zeta 1 2.40281
AVEN apoptosis, caspase activation inhibitor 2.40196
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 2.39878
CDK19 cyclin-dependent kinase 19 2.39555
ANXA9 annexin A9 2.38794
PCDHB16 protocadherin beta 16 2.38385
CTBS chitobiase, di-N-acetyl- 2.38233
RRAGC Ras-related GTP binding C 2.38036
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 2.37479
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 2.372
GPX2 glutathione peroxidase 2 2.36536
CLSTN3 calsyntenin 3 2.36246
IGF2R insulin-like growth factor 2 receptor 2.36027
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2.35749
POF1B premature ovarian failure, 1B 2.35408
TAGLN transgelin 2.3506
IRF6 interferon regulatory factor 6 2.34549
TOM1 target of myb1 (chicken) 2.34241
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.3401
ANO10 anoctamin 10 2.33551
EBI3 Epstein-Barr virus induced 3 2.32966
SPATA2L spermatogenesis associated 2-like 2.32739
KDM6A lysine (K)-specific demethylase 6A 2.32277
AKTIP AKT interacting protein 2.31999
IGHMBP2 immunoglobulin mu binding protein 2 2.31396
LPAR4 lysophosphatidic acid receptor 4 2.3116
NPC1 Niemann-Pick disease, type C1 2.31127
TFE3 transcription factor binding to IGHM enhancer 3 2.31038
VPS9D1 VPS9 domain containing 1 2.31009
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 2.30922
EFNA1 ephrin-A1 2.29953
MMP24OS MMP24 opposite strand 2.29782
MAGED2 melanoma antigen family D2 2.28852
ACBD3 acyl-CoA binding domain containing 3 2.28222
CLDN7 claudin 7 2.28182
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 2.28051
SPAG7 sperm associated antigen 7 2.27989
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 2.27802
PSG5 pregnancy specific beta-1-glycoprotein 5 2.27765
ELOVL1 ELOVL fatty acid elongase 1 2.27504
ORAI3 ORAI calcium release-activated calcium modulator 3 2.26851
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 2.26223
DDR1 discoidin domain receptor tyrosine kinase 1 2.26166
NDEL1 nudE neurodevelopment protein 1-like 1 2.26155
SMAP1 small ArfGAP 1 2.26005
TZMP1 transition zone microprotein 1 2.25722
FADS2 fatty acid desaturase 2 2.25134
PHF21A PHD finger protein 21A 2.24524
SLC67A1 solute carrier family 67 member 1 2.24124
LOC128125814 uncharacterized LOC128125814 2.24098
CXCR4 chemokine (C-X-C motif) receptor 4 2.23612
SIL1 SIL1 nucleotide exchange factor 2.23569
CCPG1 cell cycle progression 1 2.23457
AHNAK AHNAK nucleoprotein 2.23372
STX5 syntaxin 5 2.23191
OSBPL2 oxysterol binding protein-like 2 2.22911
ZNF14 zinc finger protein 14 2.22906
PHKB phosphorylase kinase, beta 2.22828
PRSS8 protease, serine, 8 2.22752
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha 2.22361
TSPYL2 TSPY-like 2 2.22001
JMJD7 jumonji domain containing 7 2.21994
PSEN1 presenilin 1 2.21843
PLCD1 phospholipase C, delta 1 2.2158
AKAP13 A kinase (PRKA) anchor protein 13 2.21352
PRAF2 PRA1 domain family, member 2 2.2133
N4BP3 NEDD4 binding protein 3 2.21324
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 2.21248
WDTC1 WD and tetratricopeptide repeats 1 2.21223
VSIG2 V-set and immunoglobulin domain containing 2 2.2112
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 2.20836
GCLM glutamate-cysteine ligase, modifier subunit 2.20752
CALCOCO1 calcium binding and coiled-coil domain 1 2.20721
NMRK1 nicotinamide riboside kinase 1 2.20296
TCEA2 transcription elongation factor A (SII), 2 2.20102
NRIP2 nuclear receptor interacting protein 2 2.19654
KLHDC2 kelch domain containing 2 2.19242
GOLGB1 golgin B1 2.18894
TALDO1 transaldolase 1 2.18618
MYBPC3 myosin binding protein C, cardiac 2.18574
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.18084
SP3 Sp3 transcription factor 2.18054
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 2.17686
FGF9 fibroblast growth factor 9 2.17439
MX2 MX dynamin-like GTPase 2 2.16793
RNF113A ring finger protein 113A 2.16622
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 2.16588
TSPAN15 tetraspanin 15 2.16578
INPPL1 inositol polyphosphate phosphatase-like 1 2.15829
YIPF6 Yip1 domain family, member 6 2.15585
PEX13 peroxisomal biogenesis factor 13 2.15282
CLDN4 claudin 4 2.15253
AKR1C3 aldo-keto reductase family 1, member C3 2.15183
GNL1 guanine nucleotide binding protein-like 1 2.15182
MAPK3 mitogen-activated protein kinase 3 2.14727
MAPK6 mitogen-activated protein kinase 6 2.13925
OSGIN1 oxidative stress induced growth inhibitor 1 2.13766
TRAFD1 TRAF-type zinc finger domain containing 1 2.13115
LCE2B late cornified envelope 2B 2.12896
CHMP1B charged multivesicular body protein 1B 2.12477
AGR2 anterior gradient 2 2.12356
VPS35L VPS35 endosomal protein sorting factor like 2.12229
GGPS1 geranylgeranyl diphosphate synthase 1 2.12203
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.12154
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 2.12108
ELMO3 engulfment and cell motility 3 2.12052
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 2.11989
NPPA natriuretic peptide A 2.11777
NFE2L1 nuclear factor, erythroid 2-like 1 2.10987
ZNF467 zinc finger protein 467 2.10959
KIAA0232 KIAA0232 2.10671
DENND2D DENN/MADD domain containing 2D 2.10186
PCCA propionyl CoA carboxylase, alpha polypeptide 2.10071
FAM8A1 family with sequence similarity 8, member A1 2.09851
DNM3 dynamin 3 2.09789
LMBRD1 LMBR1 domain containing 1 2.09452
TRIM62 tripartite motif containing 62 2.09326
SECTM1 secreted and transmembrane 1 2.09101
DPP3 dipeptidyl-peptidase 3 2.08987
PRR15L proline rich 15-like 2.08872
MB myoglobin 2.08463
GADD45B growth arrest and DNA-damage-inducible, beta 2.08325
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 2.083
NINJ1 ninjurin 1 2.07938
CLUL1 clusterin-like 1 (retinal) 2.07664
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 2.07432
SMIM29 small integral membrane protein 29 2.07392
RABAC1 Rab acceptor 1 (prenylated) 2.07162
KRT33A keratin 33A, type I 2.06928
CYB5R1 cytochrome b5 reductase 1 2.06657
HYOU1 hypoxia up-regulated 1 2.06637
TP53I3 tumor protein p53 inducible protein 3 2.06526
TCHH trichohyalin 2.06489
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 2.0644
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 2.06343
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase 2.06162
RNF170 ring finger protein 170 2.06109
WHR1 winged helix repair factor 1 2.05928
TRIM38 tripartite motif containing 38 2.05349
ZBTB22 zinc finger and BTB domain containing 22 2.05181
DXO decapping exoribonuclease 2.0475
EHD1 EH-domain containing 1 2.0473
KIAA0513 KIAA0513 2.04722
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 2.04499
MEF2D myocyte enhancer factor 2D 2.04407
CDPF1 cysteine-rich, DPF motif domain containing 1 2.04302
LYRM9 LYR motif containing 9 2.04284
RIPOR2 RHO family interacting cell polarization regulator 2 2.04279
GPC1 glypican 1 2.04108
BEST1 bestrophin 1 2.0401
STBD1 starch binding domain 1 2.03903
DCTN2 dynactin 2 (p50) 2.03433
IL32 interleukin 32 2.03346
HDAC11 histone deacetylase 11 2.03293
MAGT1 magnesium transporter 1 2.0295
APOD apolipoprotein D 2.02948
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 2.0277
RAB8B RAB8B, member RAS oncogene family 2.02674
KRT9 keratin 9, type I 2.02568
BCAS4 breast carcinoma amplified sequence 4 2.02567
RWDD2A RWD domain containing 2A 2.02334
ZSCAN16 zinc finger and SCAN domain containing 16 2.02306
STK10 serine/threonine kinase 10 2.0222
ATF3 activating transcription factor 3 2.02201
GCLC glutamate-cysteine ligase, catalytic subunit 2.02024
CARS1 cysteinyl-tRNA synthetase 1 2.0195
NRBF2 nuclear receptor binding factor 2 2.01399
RHOQ ras homolog family member Q 2.01134
PPCS phosphopantothenoylcysteine synthetase 2.01117
KRT31 keratin 31, type I 2.011
OSTF1 osteoclast stimulating factor 1 2.00834
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 2.00641
PHF13 PHD finger protein 13 2.00553
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 2.0031
SUCO SUN domain containing ossification factor 2.00178
CLCN3 chloride channel, voltage-sensitive 3 2.00158

decreased expression

Symbol Name Standardized Value
CDC45 cell division cycle 45 -5.89314
DCK deoxycytidine kinase -5.59036
NCAPH non-SMC condensin I complex, subunit H -4.96141
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -4.79781
MCM3 minichromosome maintenance complex component 3 -4.52917
CDK1 cyclin-dependent kinase 1 -4.52901
NUP85 nucleoporin 85kDa -4.45043
ZDHHC6 zinc finger, DHHC-type containing 6 -4.31017
HAT1 histone acetyltransferase 1 -4.2718
NUP93 nucleoporin 93kDa -4.2275
MCMBP minichromosome maintenance complex binding protein -4.07008
CDC6 cell division cycle 6 -3.9497
HSPA8 heat shock 70kDa protein 8 -3.94149
KIF15 kinesin family member 15 -3.91329
AURKB aurora kinase B -3.88975
PARP2 poly (ADP-ribose) polymerase 2 -3.83599
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -3.79212
OAT ornithine aminotransferase -3.78767
DNA2 DNA replication helicase/nuclease 2 -3.73192
CDC7 cell division cycle 7 -3.72352
MSH2 mutS homolog 2 -3.69713
CDK4 cyclin-dependent kinase 4 -3.69473
UBE2C ubiquitin-conjugating enzyme E2C -3.68555
POLR1G RNA polymerase I subunit G -3.67582
CDCA4 cell division cycle associated 4 -3.65457
KIF14 kinesin family member 14 -3.65224
CHAF1A chromatin assembly factor 1, subunit A (p150) -3.64565
DSCC1 DNA replication and sister chromatid cohesion 1 -3.64233
NCAPD2 non-SMC condensin I complex, subunit D2 -3.6383
PFAS phosphoribosylformylglycinamidine synthase -3.61664
FEN1 flap structure-specific endonuclease 1 -3.60846
MCM10 minichromosome maintenance complex component 10 -3.59221
PSRC1 proline/serine-rich coiled-coil 1 -3.57184
PLK1 polo-like kinase 1 -3.56873
EBNA1BP2 EBNA1 binding protein 2 -3.54645
VDAC1 voltage-dependent anion channel 1 -3.53687
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 -3.52244
NEIL3 nei endonuclease VIII-like 3 (E. coli) -3.52001
BCCIP BRCA2 and CDKN1A interacting protein -3.50736
CENPA centromere protein A -3.49025
STMN1 stathmin 1 -3.47398
TRIP13 thyroid hormone receptor interactor 13 -3.45752
FOXM1 forkhead box M1 -3.45212
RFC3 replication factor C (activator 1) 3, 38kDa -3.37068
CDCA8 cell division cycle associated 8 -3.35881
ASF1B anti-silencing function 1B histone chaperone -3.35234
BIRC5 baculoviral IAP repeat containing 5 -3.343
GINS2 GINS complex subunit 2 (Psf2 homolog) -3.30759
MCM6 minichromosome maintenance complex component 6 -3.30656
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.30097
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) -3.3006
KIF11 kinesin family member 11 -3.29281
CDCA3 cell division cycle associated 3 -3.28761
EXO1 exonuclease 1 -3.28752
BRCA1 breast cancer 1, early onset -3.28352
GMNN geminin, DNA replication inhibitor -3.27679
RPP30 ribonuclease P/MRP 30kDa subunit -3.24772
ERCC6L excision repair cross-complementation group 6-like -3.24533
CD320 CD320 molecule -3.21812
HJURP Holliday junction recognition protein -3.21701
MCM7 minichromosome maintenance complex component 7 -3.21694
ATAD2 ATPase family, AAA domain containing 2 -3.21629
CEP55 centrosomal protein 55kDa -3.21415
RAD51AP1 RAD51 associated protein 1 -3.21107
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae) -3.18621
HMG20B high mobility group 20B -3.17
SPC25 SPC25, NDC80 kinetochore complex component -3.16515
TIPIN TIMELESS interacting protein -3.15865
NOLC1 nucleolar and coiled-body phosphoprotein 1 -3.15716
PARP1 poly (ADP-ribose) polymerase 1 -3.15554
KIF18A kinesin family member 18A -3.14956
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -3.14824
CDT1 chromatin licensing and DNA replication factor 1 -3.11175
PYDC1 PYD (pyrin domain) containing 1 -3.11093
KIF20A kinesin family member 20A -3.10159
PDCD11 programmed cell death 11 -3.08924
ACOD1 aconitate decarboxylase 1 -3.07336
AURKA aurora kinase A -3.05222
SPDL1 spindle apparatus coiled-coil protein 1 -3.0502
AUNIP aurora kinase A and ninein interacting protein -3.04878
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) -3.03916
GINS3 GINS complex subunit 3 (Psf3 homolog) -3.03741
KIF4A kinesin family member 4A -3.03426
CCNF cyclin F -3.02354
PSIP1 PC4 and SFRS1 interacting protein 1 -3.0204
MCM5 minichromosome maintenance complex component 5 -3.01924
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -3.01829
NUP107 nucleoporin 107kDa -3.01243
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -3.00943
WDHD1 WD repeat and HMG-box DNA binding protein 1 -3.0012
BRIX1 BRX1, biogenesis of ribosomes -2.99687
CDC25B cell division cycle 25B -2.99614
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -2.99101
TROAP trophinin associated protein -2.9816
MKI67 marker of proliferation Ki-67 -2.9747
FANCI Fanconi anemia, complementation group I -2.97362
MCM4 minichromosome maintenance complex component 4 -2.96158
DBF4 DBF4 zinc finger -2.95188
SKA1 spindle and kinetochore associated complex subunit 1 -2.93656
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.92569
NCAPD3 non-SMC condensin II complex, subunit D3 -2.9233
RFC2 replication factor C (activator 1) 2, 40kDa -2.92173
NUP155 nucleoporin 155kDa -2.91105
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -2.90132
TWNK twinkle mtDNA helicase -2.89986
DKC1 dyskeratosis congenita 1, dyskerin -2.88635
CDC25A cell division cycle 25A -2.88522
NAT10 N-acetyltransferase 10 (GCN5-related) -2.88335
DDB2 damage-specific DNA binding protein 2, 48kDa -2.8747
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.87288
RPIA ribose 5-phosphate isomerase A -2.87245
CCNB2 cyclin B2 -2.85715
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.85713
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -2.84728
HNRNPM heterogeneous nuclear ribonucleoprotein M -2.84044
RFWD3 ring finger and WD repeat domain 3 -2.8377
WDR76 WD repeat domain 76 -2.83641
CWF19L1 CWF19-like 1, cell cycle control (S. pombe) -2.83626
HOXA5 homeobox A5 -2.81104
COL4A1 collagen, type IV, alpha 1 -2.76915
NOL9 nucleolar protein 9 -2.76664
TSEN2 TSEN2 tRNA splicing endonuclease subunit -2.75678
BYSL bystin-like -2.75635
PWP2 PWP2 periodic tryptophan protein homolog (yeast) -2.75452
KIF18B kinesin family member 18B -2.73268
RPA3 replication protein A3, 14kDa -2.71325
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) -2.70615
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -2.69898
NHLRC2 NHL repeat containing 2 -2.65636
KIFBP kinesin family binding protein -2.6462
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa -2.64232
MIS18A MIS18 kinetochore protein A -2.63428
TUBB6 tubulin, beta 6 class V -2.62555
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.62168
CCNA2 cyclin A2 -2.62026
GRWD1 glutamate-rich WD repeat containing 1 -2.61551
KIF23 kinesin family member 23 -2.61241
HAUS7 HAUS augmin-like complex, subunit 7 -2.60253
FBXO5 F-box protein 5 -2.60042
PUS1 pseudouridylate synthase 1 -2.59888
PIMREG PICALM interacting mitotic regulator -2.59857
PA2G4 proliferation-associated 2G4, 38kDa -2.59633
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -2.59501
PRPF31 pre-mRNA processing factor 31 -2.58909
CHEK1 checkpoint kinase 1 -2.58772
USP1 ubiquitin specific peptidase 1 -2.58736
NUSAP1 nucleolar and spindle associated protein 1 -2.58651
WDR3 WD repeat domain 3 -2.57986
CCNB1 cyclin B1 -2.57483
EXOSC5 exosome component 5 -2.55608
RECQL4 RecQ protein-like 4 -2.55413
TACC3 transforming, acidic coiled-coil containing protein 3 -2.55273
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -2.54923
NEK2 NIMA-related kinase 2 -2.54011
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -2.53877
TEDC2 tubulin epsilon and delta complex 2 -2.53437
WDR77 WD repeat domain 77 -2.53167
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.5221
TOP2A topoisomerase (DNA) II alpha 170kDa -2.51847
EXOSC9 exosome component 9 -2.4997
CDC20 cell division cycle 20 -2.49134
THAP11 THAP domain containing 11 -2.48598
SLC35F2 solute carrier family 35, member F2 -2.48303
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.48213
PTPN3 protein tyrosine phosphatase, non-receptor type 3 -2.47605
OIP5 Opa interacting protein 5 -2.46052
COL4A2 collagen, type IV, alpha 2 -2.45283
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.44393
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase -2.44122
ADGRA3 adhesion G protein-coupled receptor A3 -2.43683
BUB3 BUB3 mitotic checkpoint protein -2.4347
NUP205 nucleoporin 205kDa -2.43298
XPO6 exportin 6 -2.42374
ZNF143 zinc finger protein 143 -2.41728
TCOF1 Treacher Collins-Franceschetti syndrome 1 -2.41379
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -2.41009
SRSF2 serine/arginine-rich splicing factor 2 -2.40661
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -2.40579
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -2.39678
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 -2.39265
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.39203
DSN1 DSN1, MIS12 kinetochore complex component -2.38719
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase -2.38703
C1QBP complement component 1, q subcomponent binding protein -2.38598
DONSON downstream neighbor of SON -2.3831
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa -2.3801
PRPF4 pre-mRNA processing factor 4 -2.37774
TCERG1 transcription elongation regulator 1 -2.37633
TMEM109 transmembrane protein 109 -2.37157
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -2.3683
WBP11 WW domain binding protein 11 -2.36635
BLM Bloom syndrome, RecQ helicase-like -2.36282
TRIM28 tripartite motif containing 28 -2.36233
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -2.34987
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -2.34034
GGCT gamma-glutamylcyclotransferase -2.33446
PUF60 poly-U binding splicing factor 60KDa -2.33071
NUP62 nucleoporin 62kDa -2.32722
CCDC86 coiled-coil domain containing 86 -2.3218
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.31605
NPM3 nucleophosmin/nucleoplasmin 3 -2.30926
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -2.30894
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) -2.30782
PHF10 PHD finger protein 10 -2.30131
BORA bora, aurora kinase A activator -2.29968
CS citrate synthase -2.2968
NLE1 notchless homolog 1 (Drosophila) -2.29387
CKLF-CMTM1 CKLF-CMTM1 readthrough -2.29292
PSMC3IP PSMC3 interacting protein -2.28998
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -2.28769
STAC SH3 and cysteine rich domain -2.27821
TUBG1 tubulin, gamma 1 -2.27596
TIMCC TIM double twin CX3C motif chaperone -2.26387
SMYD5 SMYD family member 5 -2.25618
CCP110 centriolar coiled coil protein 110kDa -2.25605
TDP1 tyrosyl-DNA phosphodiesterase 1 -2.2554
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.2533
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.24683
TEX30 testis expressed 30 -2.2462
TUBGCP4 tubulin, gamma complex associated protein 4 -2.24326
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) -2.23749
GEMIN4 gem (nuclear organelle) associated protein 4 -2.22723
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -2.22576
NOP16 NOP16 nucleolar protein -2.22129
PCNA proliferating cell nuclear antigen -2.22049
PRPF8 pre-mRNA processing factor 8 -2.21351
FOS FBJ murine osteosarcoma viral oncogene homolog -2.2093
RUVBL1 RuvB-like AAA ATPase 1 -2.20862
PBK PDZ binding kinase -2.20809
ENOX1 ecto-NOX disulfide-thiol exchanger 1 -2.20443
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9 -2.20423
PUM3 pumilio RNA binding family member 3 -2.20373
MRM2 mitochondrial rRNA methyltransferase 2 -2.20366
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -2.1998
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.19889
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa -2.19656
POLE polymerase (DNA directed), epsilon, catalytic subunit -2.19604
KNTC1 kinetochore associated 1 -2.19435
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -2.19241
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.1882
ZNF22 zinc finger protein 22 -2.18607
SMC3 structural maintenance of chromosomes 3 -2.18259
MSH6 mutS homolog 6 -2.18021
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -2.17571
EXOSC10 exosome component 10 -2.17532
SLF2 SMC5-SMC6 complex localization factor 2 -2.16132
NOL11 nucleolar protein 11 -2.15662
SLBP stem-loop binding protein -2.15517
HLTF helicase-like transcription factor -2.15406
PLK4 polo-like kinase 4 -2.1482
RFC4 replication factor C (activator 1) 4, 37kDa -2.14569
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -2.14389
AP3M2 adaptor-related protein complex 3, mu 2 subunit -2.1424
HDAC2 histone deacetylase 2 -2.1381
FHL2 four and a half LIM domains 2 -2.13022
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) -2.13019
PTTG1 pituitary tumor-transforming 1 -2.12812
THOP1 thimet oligopeptidase 1 -2.12779
CENPM centromere protein M -2.12773
POLR1D polymerase (RNA) I polypeptide D, 16kDa -2.12764
GPSM2 G-protein signaling modulator 2 -2.12731
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa -2.12571
SHCBP1 SHC SH2-domain binding protein 1 -2.1247
PNN pinin, desmosome associated protein -2.12384
RBL1 retinoblastoma-like 1 -2.12334
PRPF38B pre-mRNA processing factor 38B -2.12231
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -2.12201
CENPQ centromere protein Q -2.12036
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) -2.12023
ORC6 origin recognition complex, subunit 6 -2.11882
ARHGAP11A Rho GTPase activating protein 11A -2.11722
CMC2 C-x(9)-C motif containing 2 -2.11678
FERRY3 FERRY endosomal RAB5 effector complex subunit 3 -2.11581
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) -2.11343
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -2.11108
NASP nuclear autoantigenic sperm protein (histone-binding) -2.1103
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.10602
OSBPL3 oxysterol binding protein-like 3 -2.10551
ARMC1 armadillo repeat containing 1 -2.10536
RPL39L ribosomal protein L39-like -2.10286
ILF2 interleukin enhancer binding factor 2 -2.10245
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 -2.09722
EIF3D eukaryotic translation initiation factor 3, subunit D -2.09508
HGH1 HGH1 homolog (S. cerevisiae) -2.09288
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -2.09274
DCLRE1A DNA cross-link repair 1A -2.09117
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -2.08909
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -2.08813
AK8 adenylate kinase 8 -2.08336
USP22 ubiquitin specific peptidase 22 -2.0829
GINS4 GINS complex subunit 4 (Sld5 homolog) -2.08267
GLOD4 glyoxalase domain containing 4 -2.08027
CCT8 chaperonin containing TCP1, subunit 8 (theta) -2.07845
ZNF232 zinc finger protein 232 -2.0758
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.07208
DNAAF5 dynein, axonemal, assembly factor 5 -2.07103
CENPN centromere protein N -2.07102
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -2.06682
MYC v-myc avian myelocytomatosis viral oncogene homolog -2.0636
ZBED2 zinc finger, BED-type containing 2 -2.0609
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -2.05756
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -2.05686
ICE1 interactor of little elongation complex ELL subunit 1 -2.05446
CENPI centromere protein I -2.04945
UNG uracil-DNA glycosylase -2.04843
SMC4 structural maintenance of chromosomes 4 -2.04154
ENY2 enhancer of yellow 2 homolog (Drosophila) -2.04152
MAK16 MAK16 homolog (S. cerevisiae) -2.03966
OBI1 ORC ubiquitin ligase 1 -2.03769
UXT ubiquitously-expressed, prefoldin-like chaperone -2.03497
MRPL3 mitochondrial ribosomal protein L3 -2.03332
KDM1A lysine (K)-specific demethylase 1A -2.03189
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 -2.03082
HIRIP3 HIRA interacting protein 3 -2.0278
SCRIB scribbled planar cell polarity protein -2.02396
ENTR1 endosome associated trafficking regulator 1 -2.0209
DHFR dihydrofolate reductase -2.01844
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 -2.01205
SNRPA small nuclear ribonucleoprotein polypeptide A -2.01147
RACGAP1 Rac GTPase activating protein 1 -2.00932
HAUS6 HAUS augmin-like complex, subunit 6 -2.00607
COLGALT1 collagen beta(1-O)galactosyltransferase 1 -2.00549
UBA2 ubiquitin-like modifier activating enzyme 2 -2.00502
SF3A2 splicing factor 3a, subunit 2, 66kDa -2.00334
ACYP1 acylphosphatase 1, erythrocyte (common) type -2.00135