CRCGN017_MCF10A.TP53.M_24H:J06 Gene Set
Genes
43 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:J06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HMOX1
|
heme oxygenase 1
|
6.2153
|
|
TXNRD1
|
thioredoxin reductase 1
|
5.33673
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
5.0329
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.87226
|
|
RBP4
|
retinol binding protein 4, plasma
|
3.5488
|
|
AGR2
|
anterior gradient 2
|
3.25057
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
2.99286
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.90336
|
|
ABHD4
|
abhydrolase domain containing 4
|
2.73468
|
|
TRIM16
|
tripartite motif containing 16
|
2.68673
|
|
TP53I3
|
tumor protein p53 inducible protein 3
|
2.45617
|
|
CAPN1
|
calpain 1, (mu/I) large subunit
|
2.42367
|
|
TRAK2
|
trafficking protein, kinesin binding 2
|
2.42135
|
|
ALDH3A1
|
aldehyde dehydrogenase 3 family, member A1
|
2.41174
|
|
TIRAP
|
toll-interleukin 1 receptor (TIR) domain containing adaptor protein
|
2.32391
|
|
NQO1
|
NAD(P)H dehydrogenase, quinone 1
|
2.31383
|
|
PIR
|
pirin (iron-binding nuclear protein)
|
2.28562
|
|
STK16
|
serine/threonine kinase 16
|
2.27709
|
|
MUC1
|
mucin 1, cell surface associated
|
2.27187
|
|
PITPNM1
|
phosphatidylinositol transfer protein, membrane-associated 1
|
2.26304
|
|
ACBD3
|
acyl-CoA binding domain containing 3
|
2.17381
|
|
NMRK1
|
nicotinamide riboside kinase 1
|
2.06899
|
|
WASHC3
|
WASH complex subunit 3
|
2.06194
|
|
LRP5
|
low density lipoprotein receptor-related protein 5
|
2.02678
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
KRT14
|
keratin 14, type I
|
-5.89422
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-4.66325
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
-4.06785
|
|
SCYL3
|
SCY1-like 3 (S. cerevisiae)
|
-3.8789
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.94348
|
|
ISOC1
|
isochorismatase domain containing 1
|
-2.81951
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
-2.64979
|
|
DUSP6
|
dual specificity phosphatase 6
|
-2.5271
|
|
THAP11
|
THAP domain containing 11
|
-2.50724
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.43802
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.36096
|
|
CDC7
|
cell division cycle 7
|
-2.2488
|
|
UBN1
|
ubinuclein 1
|
-2.24736
|
|
PAQR4
|
progestin and adipoQ receptor family member IV
|
-2.24359
|
|
TTI1
|
TELO2 interacting protein 1
|
-2.2207
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.16225
|
|
HMOX2
|
heme oxygenase 2
|
-2.15734
|
|
GRN
|
granulin
|
-2.11015
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
-2.06879
|
