CRCGN017_MCF10A.TP53.M_24H:J07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description oxytetracycline.hcl 99.8 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

594 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:J07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GFPT1 glutamine--fructose-6-phosphate transaminase 1 8.59476
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 8.49465
AGR2 anterior gradient 2 8.36354
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 8.16525
PYCR1 pyrroline-5-carboxylate reductase 1 7.39749
TXNRD1 thioredoxin reductase 1 6.74462
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 6.48081
TRIB3 tribbles pseudokinase 3 6.33178
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 6.20687
GARS1 glycyl-tRNA synthetase 1 6.13929
ATF4 activating transcription factor 4 5.95484
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 5.92982
AARS1 alanyl-tRNA synthetase 1 5.85316
CXCL2 chemokine (C-X-C motif) ligand 2 5.76228
GLRX glutaredoxin (thioltransferase) 5.56567
ASNS asparagine synthetase (glutamine-hydrolyzing) 5.55526
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 5.50899
CTSL cathepsin L 5.3318
NUCB2 nucleobindin 2 5.25332
FYN FYN proto-oncogene, Src family tyrosine kinase 5.22936
HBA1 hemoglobin, alpha 1 5.10473
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 5.07177
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 5.00375
PHGDH phosphoglycerate dehydrogenase 4.94701
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 4.93922
LOC128125814 uncharacterized LOC128125814 4.88778
PSAT1 phosphoserine aminotransferase 1 4.85437
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 4.78578
CARS1 cysteinyl-tRNA synthetase 1 4.75266
VSIG2 V-set and immunoglobulin domain containing 2 4.69596
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 4.55887
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 4.53947
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 4.50049
UBQLN2 ubiquilin 2 4.47523
GRB10 growth factor receptor-bound protein 10 4.39897
IL1B interleukin 1, beta 4.38426
CHIC2 cysteine-rich hydrophobic domain 2 4.31144
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 4.29902
XPOT exportin, tRNA 4.27656
FKBP14 FK506 binding protein 14, 22 kDa 4.27088
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 4.20103
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 4.16661
ECH1 enoyl CoA hydratase 1, peroxisomal 4.15761
SARS1 seryl-tRNA synthetase 1 4.01136
TES testin LIM domain protein 4.01069
EGR1 early growth response 1 3.99566
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 3.93031
CCNA1 cyclin A1 3.86988
WARS1 tryptophanyl-tRNA synthetase 1 3.74556
CHMP4B charged multivesicular body protein 4B 3.74388
SCFD1 sec1 family domain containing 1 3.7357
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 3.73141
SLC35B1 solute carrier family 35, member B1 3.71452
WIF1 WNT inhibitory factor 1 3.69552
GAA glucosidase, alpha; acid 3.6479
MARS1 methionyl-tRNA synthetase 1 3.64583
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 3.53013
P3H1 prolyl 3-hydroxylase 1 3.52096
IFRD1 interferon-related developmental regulator 1 3.51919
HMOX1 heme oxygenase 1 3.51234
UFM1 ubiquitin-fold modifier 1 3.49874
TRIB1 tribbles pseudokinase 1 3.48733
EPRS1 glutamyl-prolyl-tRNA synthetase 1 3.46402
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 3.43974
TARS1 threonyl-tRNA synthetase 1 3.42028
FHL2 four and a half LIM domains 2 3.38495
UGDH UDP-glucose 6-dehydrogenase 3.38326
YARS1 tyrosyl-tRNA synthetase 1 3.36393
LARP6 La ribonucleoprotein domain family, member 6 3.33103
DDIT4 DNA-damage-inducible transcript 4 3.29188
NARS1 asparaginyl-tRNA synthetase 1 3.26301
TMEM39A transmembrane protein 39A 3.2222
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 3.21876
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 3.21025
PGM3 phosphoglucomutase 3 3.17923
HAX1 HCLS1 associated protein X-1 3.1662
RBKS ribokinase 3.15621
INHBE inhibin, beta E 3.13345
G0S2 G0/G1 switch 2 3.08732
SQSTM1 sequestosome 1 3.08141
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 3.06347
STC2 stanniocalcin 2 3.05474
CALU calumenin 3.05159
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 3.04779
CXCL3 chemokine (C-X-C motif) ligand 3 3.01801
ZCCHC8 zinc finger, CCHC domain containing 8 2.99122
NRBF2 nuclear receptor binding factor 2 2.99037
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 2.96997
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 2.94288
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough 2.94169
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.93155
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 2.93011
IER3 immediate early response 3 2.92619
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 2.92533
SPAG4 sperm associated antigen 4 2.92299
SIL1 SIL1 nucleotide exchange factor 2.91575
TBPL1 TBP-like 1 2.91253
PRAF2 PRA1 domain family, member 2 2.91093
EGR3 early growth response 3 2.88491
MOSPD2 motile sperm domain containing 2 2.88246
ARCN1 archain 1 2.86692
ARMCX3 armadillo repeat containing, X-linked 3 2.82964
CXCL5 chemokine (C-X-C motif) ligand 5 2.82908
GOLGA3 golgin A3 2.81202
IL21R interleukin 21 receptor 2.78277
IFT88 intraflagellar transport 88 2.77534
ERP29 endoplasmic reticulum protein 29 2.77374
STAMBP STAM binding protein 2.76111
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 2.7596
ATF6 activating transcription factor 6 2.72937
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 2.72638
AMZ2 archaelysin family metallopeptidase 2 2.72244
BDNF brain-derived neurotrophic factor 2.71773
SLC31A1 solute carrier family 31 (copper transporter), member 1 2.69418
CNIH1 cornichon family AMPA receptor auxiliary protein 1 2.6908
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.68584
TTC17 tetratricopeptide repeat domain 17 2.67662
NIT1 nitrilase 1 2.66297
ODR4 odr-4 GPCR localization factor homolog 2.65869
HYOU1 hypoxia up-regulated 1 2.65401
P4HB prolyl 4-hydroxylase, beta polypeptide 2.64714
AGA aspartylglucosaminidase 2.64294
LAX1 lymphocyte transmembrane adaptor 1 2.63777
GMPPA GDP-mannose pyrophosphorylase A 2.63768
TERF2IP telomeric repeat binding factor 2, interacting protein 2.62715
VEGFC vascular endothelial growth factor C 2.62065
MAGED2 melanoma antigen family D2 2.60336
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.6032
PLAUR plasminogen activator, urokinase receptor 2.60289
SCCPDH saccharopine dehydrogenase (putative) 2.58381
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 2.57652
FOSL1 FOS-like antigen 1 2.56482
CEMIP cell migration inducing protein, hyaluronan binding 2.56012
KIF3B kinesin family member 3B 2.55978
CAMTA2 calmodulin binding transcription activator 2 2.55541
CDPF1 cysteine-rich, DPF motif domain containing 1 2.55493
METTL25B methyltransferase like 25B 2.55283
SEC63 SEC63 homolog (S. cerevisiae) 2.55235
AKAP17A A kinase (PRKA) anchor protein 17A 2.53286
JMJD1C jumonji domain containing 1C 2.53095
PDGFA platelet-derived growth factor alpha polypeptide 2.52991
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 2.5165
IL1A interleukin 1, alpha 2.51514
TBL1X transducin (beta)-like 1X-linked 2.51031
CCPG1 cell cycle progression 1 2.50471
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2.4943
GOLT1B golgi transport 1B 2.48858
MID1IP1 MID1 interacting protein 1 2.48335
ZFP69B ZFP69 zinc finger protein B 2.46765
DHRS7 dehydrogenase/reductase (SDR family) member 7 2.46468
SLC30A1 solute carrier family 30 (zinc transporter), member 1 2.4619
ZBTB11 zinc finger and BTB domain containing 11 2.45756
SMIM10L1 small integral membrane protein 10 like 1 2.45522
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 2.45212
COPB1 coatomer protein complex, subunit beta 1 2.45199
ANKRD11 ankyrin repeat domain 11 2.44495
ACSS3 acyl-CoA synthetase short-chain family member 3 2.44444
GORASP2 golgi reassembly stacking protein 2, 55kDa 2.44258
GALE UDP-galactose-4-epimerase 2.43431
COLGALT2 collagen beta(1-O)galactosyltransferase 2 2.43359
GOLT1A golgi transport 1A 2.41813
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.41456
CTBS chitobiase, di-N-acetyl- 2.41443
ARID4B AT rich interactive domain 4B (RBP1-like) 2.4115
HSPA13 heat shock protein 70kDa family, member 13 2.41075
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 2.40961
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 2.40787
GTPBP2 GTP binding protein 2 2.3931
TESC tescalcin 2.39128
H1-0 H1.0 linker histone 2.38727
ZNF84 zinc finger protein 84 2.38528
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 2.38409
IARS1 isoleucyl-tRNA synthetase 1 2.38115
NDEL1 nudE neurodevelopment protein 1-like 1 2.37851
MOAP1 modulator of apoptosis 1 2.37777
LOC102724560 cystathionine beta-synthase 2.37245
HBEGF heparin-binding EGF-like growth factor 2.37079
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 2.36935
SLC38A2 solute carrier family 38, member 2 2.36766
BMP4 bone morphogenetic protein 4 2.36575
TMEM131 transmembrane protein 131 2.36325
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 2.35666
ZNF410 zinc finger protein 410 2.35605
RWDD2A RWD domain containing 2A 2.34759
SERINC1 serine incorporator 1 2.34727
AKTIP AKT interacting protein 2.33718
ZMYM2 zinc finger, MYM-type 2 2.33491
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 2.33408
ACADVL acyl-CoA dehydrogenase, very long chain 2.32869
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 2.32474
ZMAT3 zinc finger, matrin-type 3 2.31949
SETD5 SET domain containing 5 2.31606
GCC2 GRIP and coiled-coil domain containing 2 2.31456
IFT20 intraflagellar transport 20 2.31233
CEP57 centrosomal protein 57kDa 2.31212
ZPR1 ZPR1 zinc finger 2.30994
ALAS1 5'-aminolevulinate synthase 1 2.30884
LRP10 low density lipoprotein receptor-related protein 10 2.30672
SIAH2 siah E3 ubiquitin protein ligase 2 2.29784
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 2.29542
AZIN2 antizyme inhibitor 2 2.29444
CNRIP1 cannabinoid receptor interacting protein 1 2.29034
RNF103 ring finger protein 103 2.28928
ETHE1 ethylmalonic encephalopathy 1 2.28796
NAT9 N-acetyltransferase 9 (GCN5-related, putative) 2.28196
MYDGF myeloid-derived growth factor 2.28044
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.2787
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog 2.27452
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.27046
JTB jumping translocation breakpoint 2.2683
STK10 serine/threonine kinase 10 2.26164
LIN7A lin-7 homolog A (C. elegans) 2.25418
UFL1 UFM1-specific ligase 1 2.25244
USP21 ubiquitin specific peptidase 21 2.25205
HBB hemoglobin, beta 2.25196
STX1A syntaxin 1A (brain) 2.24571
CSF3R colony stimulating factor 3 receptor (granulocyte) 2.24089
RPN2 ribophorin II 2.23982
PCCB propionyl CoA carboxylase, beta polypeptide 2.2316
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 2.231
LAMB3 laminin, beta 3 2.22567
USO1 USO1 vesicle transport factor 2.22484
VPS9D1 VPS9 domain containing 1 2.22449
MRPS16 mitochondrial ribosomal protein S16 2.21828
MYLK myosin light chain kinase 2.21504
NCK2 NCK adaptor protein 2 2.21326
SEC24A SEC24 family member A 2.21096
RMDN1 regulator of microtubule dynamics 1 2.20419
SYNGAP1 synaptic Ras GTPase activating protein 1 2.20401
AQP9 aquaporin 9 2.20218
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 2.19718
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.19546
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa 2.19069
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 2.18385
CREB5 cAMP responsive element binding protein 5 2.17596
TGFBI transforming growth factor, beta-induced, 68kDa 2.17196
MTMR6 myotubularin related protein 6 2.16885
MED8 mediator complex subunit 8 2.16527
MTIF2 mitochondrial translational initiation factor 2 2.1627
NPC1 Niemann-Pick disease, type C1 2.15759
BANK1 B-cell scaffold protein with ankyrin repeats 1 2.14905
EMC7 ER membrane protein complex subunit 7 2.14377
MAN2A1 mannosidase, alpha, class 2A, member 1 2.14179
NLRP4 NLR family, pyrin domain containing 4 2.13887
SEC24D SEC24 family member D 2.13637
NGLY1 N-glycanase 1 2.13628
ARF4 ADP-ribosylation factor 4 2.13627
LOC122526780 uncharacterized LOC122526780 2.13001
LOXL1 lysyl oxidase-like 1 2.12816
HDLBP high density lipoprotein binding protein 2.12529
STX8 syntaxin 8 2.12521
AKIRIN1 akirin 1 2.1213
CKAP4 cytoskeleton-associated protein 4 2.12129
DHRS4 dehydrogenase/reductase (SDR family) member 4 2.1207
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.1183
SCG5 secretogranin V 2.11784
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 2.11781
LMO4 LIM domain only 4 2.1136
NUBPL nucleotide binding protein-like 2.10723
CREB3L2 cAMP responsive element binding protein 3-like 2 2.09937
VRK2 vaccinia related kinase 2 2.09011
EIF1 eukaryotic translation initiation factor 1 2.08812
HHIPL2 HHIP-like 2 2.08417
RNF220 ring finger protein 220 2.08351
PHF20L1 PHD finger protein 20-like 1 2.08072
SLC35G2 solute carrier family 35, member G2 2.07666
S100A12 S100 calcium binding protein A12 2.07663
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.07402
MARCHF5 membrane associated ring-CH-type finger 5 2.07295
RNF170 ring finger protein 170 2.07128
CHGB chromogranin B 2.06565
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 2.06475
TBCB tubulin folding cofactor B 2.05839
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 2.05633
MANBA mannosidase, beta A, lysosomal 2.05507
CALCOCO2 calcium binding and coiled-coil domain 2 2.05474
WBP4 WW domain binding protein 4 2.0546
SERP1 stress-associated endoplasmic reticulum protein 1 2.0544
TRIP12 thyroid hormone receptor interactor 12 2.05373
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 2.0501
AMPH amphiphysin 2.04485
MBD5 methyl-CpG binding domain protein 5 2.03949
ZNF419 zinc finger protein 419 2.0354
METTL22 methyltransferase like 22 2.03419
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 2.03202
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 2.0289
RNF34 ring finger protein 34, E3 ubiquitin protein ligase 2.02662
PTPRE protein tyrosine phosphatase, receptor type, E 2.02653
CCS copper chaperone for superoxide dismutase 2.02649
MIDEAS mitotic deacetylase associated SANT domain protein 2.02568
FICD FIC domain containing 2.02519
GABARAP GABA(A) receptor-associated protein 2.02061
ABI2 abl-interactor 2 2.0175
FKBP11 FK506 binding protein 11, 19 kDa 2.00643
MLYCD malonyl-CoA decarboxylase 2.00605

decreased expression

Symbol Name Standardized Value
S100A4 S100 calcium binding protein A4 -7.19181
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -6.37627
CDC45 cell division cycle 45 -5.76195
HSPB1 heat shock 27kDa protein 1 -5.40255
KIF20A kinesin family member 20A -5.09447
PSRC1 proline/serine-rich coiled-coil 1 -5.01618
STMN1 stathmin 1 -4.89772
INSIG1 insulin induced gene 1 -4.52356
CCDC86 coiled-coil domain containing 86 -4.37981
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -4.29209
GINS3 GINS complex subunit 3 (Psf3 homolog) -4.2691
HOXA5 homeobox A5 -4.25937
ANKRD10 ankyrin repeat domain 10 -4.24483
CDK1 cyclin-dependent kinase 1 -4.07816
BIRC5 baculoviral IAP repeat containing 5 -4.02608
SH3D19 SH3 domain containing 19 -3.95878
ALDOC aldolase C, fructose-bisphosphate -3.83643
RGS2 regulator of G-protein signaling 2 -3.74686
ERCC6L excision repair cross-complementation group 6-like -3.74609
ELOVL6 ELOVL fatty acid elongase 6 -3.71942
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.71844
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -3.65986
ADRB2 adrenoceptor beta 2, surface -3.65317
RPA3 replication protein A3, 14kDa -3.56834
NSDHL NAD(P) dependent steroid dehydrogenase-like -3.54509
FEN1 flap structure-specific endonuclease 1 -3.52174
MSMO1 methylsterol monooxygenase 1 -3.48657
ANXA2 annexin A2 -3.47245
SESN1 sestrin 1 -3.46372
SQOR sulfide quinone oxidoreductase -3.45643
BAG3 BCL2-associated athanogene 3 -3.35896
PRR15L proline rich 15-like -3.35735
CCNB1 cyclin B1 -3.34942
DCK deoxycytidine kinase -3.34743
FKBP5 FK506 binding protein 5 -3.34301
TMEM109 transmembrane protein 109 -3.34024
UBE2C ubiquitin-conjugating enzyme E2C -3.33447
PYDC1 PYD (pyrin domain) containing 1 -3.32896
ASF1B anti-silencing function 1B histone chaperone -3.32516
CCNF cyclin F -3.27812
OAT ornithine aminotransferase -3.26752
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -3.2457
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -3.21649
GLO1 glyoxalase I -3.2158
NUP93 nucleoporin 93kDa -3.21057
NUSAP1 nucleolar and spindle associated protein 1 -3.20301
CENPM centromere protein M -3.17387
SPC25 SPC25, NDC80 kinetochore complex component -3.15706
CIAPIN1 cytokine induced apoptosis inhibitor 1 -3.11388
STAP2 signal transducing adaptor family member 2 -3.10492
CDK2 cyclin-dependent kinase 2 -3.09825
BZW2 basic leucine zipper and W2 domains 2 -3.09417
HOXA4 homeobox A4 -3.07884
OIP5 Opa interacting protein 5 -3.04826
SMNDC1 survival motor neuron domain containing 1 -3.04386
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like -3.02084
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -3.01774
SRSF3 serine/arginine-rich splicing factor 3 -3.01499
GMNN geminin, DNA replication inhibitor -3.0105
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -3.00572
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.99048
CCNA2 cyclin A2 -2.98448
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -2.98043
SYNE2 spectrin repeat containing, nuclear envelope 2 -2.97724
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.97497
MVD mevalonate (diphospho) decarboxylase -2.96884
TCEA2 transcription elongation factor A (SII), 2 -2.96063
CAB39 calcium binding protein 39 -2.93709
ARHGAP15 Rho GTPase activating protein 15 -2.93302
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa -2.93056
CPNE3 copine III -2.90645
EMP2 epithelial membrane protein 2 -2.89128
CD207 CD207 molecule, langerin -2.88898
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.88625
FGFBP1 fibroblast growth factor binding protein 1 -2.87617
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -2.85077
SHMT1 serine hydroxymethyltransferase 1 (soluble) -2.85001
CD320 CD320 molecule -2.83932
SRSF2 serine/arginine-rich splicing factor 2 -2.83233
KRT15 keratin 15, type I -2.81337
PARPBP PARP1 binding protein -2.80273
ESRP2 epithelial splicing regulatory protein 2 -2.79329
NEIL3 nei endonuclease VIII-like 3 (E. coli) -2.77605
GPD1L glycerol-3-phosphate dehydrogenase 1-like -2.76673
GPR88 G protein-coupled receptor 88 -2.75951
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 -2.74039
RFC3 replication factor C (activator 1) 3, 38kDa -2.72839
FGFR3 fibroblast growth factor receptor 3 -2.71455
DNM1 dynamin 1 -2.70214
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.70175
AMDHD2 amidohydrolase domain containing 2 -2.70036
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -2.68745
CYCS cytochrome c, somatic -2.68079
CCND3 cyclin D3 -2.66344
CAV1 caveolin 1, caveolae protein, 22kDa -2.64708
KDM3B lysine (K)-specific demethylase 3B -2.63723
TK1 thymidine kinase 1, soluble -2.61478
TSPAN6 tetraspanin 6 -2.61344
HMGB2 high mobility group box 2 -2.60449
MCM6 minichromosome maintenance complex component 6 -2.60269
WDR77 WD repeat domain 77 -2.60111
MTA2 metastasis associated 1 family, member 2 -2.60052
CDK9 cyclin-dependent kinase 9 -2.59865
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific -2.58911
INCENP inner centromere protein antigens 135/155kDa -2.58871
CRYZ crystallin, zeta (quinone reductase) -2.58685
KIF18B kinesin family member 18B -2.58451
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -2.57653
POLR2H polymerase (RNA) II (DNA directed) polypeptide H -2.57526
GRWD1 glutamate-rich WD repeat containing 1 -2.56016
PGAM4 phosphoglycerate mutase family member 4 -2.55293
RTL10 retrotransposon Gag like 10 -2.54941
B4GAT1 beta-1,4-glucuronyltransferase 1 -2.5458
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.53961
TMEM14A transmembrane protein 14A -2.53952
DYNLT3 dynein, light chain, Tctex-type 3 -2.53143
CDCA3 cell division cycle associated 3 -2.53021
CDC20 cell division cycle 20 -2.52882
RAD54L RAD54-like (S. cerevisiae) -2.52831
MCM7 minichromosome maintenance complex component 7 -2.52484
AURKB aurora kinase B -2.51825
SOAT2 sterol O-acyltransferase 2 -2.51591
NT5DC2 5'-nucleotidase domain containing 2 -2.51449
MCM10 minichromosome maintenance complex component 10 -2.51098
PPP2R5D protein phosphatase 2, regulatory subunit B', delta -2.50427
SREBF2 sterol regulatory element binding transcription factor 2 -2.50396
HADH hydroxyacyl-CoA dehydrogenase -2.50362
ZNF274 zinc finger protein 274 -2.49697
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -2.49522
CRIPT cysteine-rich PDZ-binding protein -2.49373
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A -2.48551
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) -2.47614
TMPO thymopoietin -2.47243
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -2.47114
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.46652
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -2.46162
MYO19 myosin XIX -2.46121
NAP1L4 nucleosome assembly protein 1-like 4 -2.45305
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.45193
CCNK cyclin K -2.44779
ACLY ATP citrate lyase -2.44644
MAP3K10 mitogen-activated protein kinase kinase kinase 10 -2.44243
TTLL12 tubulin tyrosine ligase-like family member 12 -2.44229
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.441
ZNF207 zinc finger protein 207 -2.43908
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 -2.43891
HOXC6 homeobox C6 -2.43313
STAU2 staufen double-stranded RNA binding protein 2 -2.43051
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 -2.4299
IGSF3 immunoglobulin superfamily, member 3 -2.42964
PBK PDZ binding kinase -2.42488
VAV3 vav 3 guanine nucleotide exchange factor -2.41873
NELFCD negative elongation factor complex member C/D -2.41763
CAV2 caveolin 2 -2.40726
MTHFSD methenyltetrahydrofolate synthetase domain containing -2.39359
DHCR24 24-dehydrocholesterol reductase -2.39306
ANGPTL7 angiopoietin-like 7 -2.39198
MRPL44 mitochondrial ribosomal protein L44 -2.38982
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa -2.38851
SH3GLB2 SH3-domain GRB2-like endophilin B2 -2.38488
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -2.37171
MCM5 minichromosome maintenance complex component 5 -2.36454
TRIP13 thyroid hormone receptor interactor 13 -2.35501
SLIT2 slit homolog 2 (Drosophila) -2.35014
FUBP3 far upstream element (FUSE) binding protein 3 -2.34967
TMEM160 transmembrane protein 160 -2.3486
CCDC25 coiled-coil domain containing 25 -2.34483
NCAPD3 non-SMC condensin II complex, subunit D3 -2.33948
SORBS3 sorbin and SH3 domain containing 3 -2.3281
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -2.32637
MCM3 minichromosome maintenance complex component 3 -2.32093
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -2.31683
BAHCC1 BAH domain and coiled-coil containing 1 -2.31245
FAM32A family with sequence similarity 32, member A -2.31184
HMGB1 high mobility group box 1 -2.30787
DNA2 DNA replication helicase/nuclease 2 -2.30703
AURKA aurora kinase A -2.30304
NUP160 nucleoporin 160kDa -2.29644
DHFR dihydrofolate reductase -2.29612
ELAC2 elaC ribonuclease Z 2 -2.29451
MRPL12 mitochondrial ribosomal protein L12 -2.29211
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -2.28736
TUBA4A tubulin, alpha 4a -2.28687
H1-4 H1.4 linker histone, cluster member -2.28297
NUP85 nucleoporin 85kDa -2.27657
PIMREG PICALM interacting mitotic regulator -2.27516
MIS18A MIS18 kinetochore protein A -2.26592
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa -2.24744
ARRB1 arrestin, beta 1 -2.24161
TBC1D10C TBC1 domain family, member 10C -2.2395
KIF11 kinesin family member 11 -2.23908
FAM234B family with sequence similarity 234 member B -2.23588
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -2.2343
ZDHHC6 zinc finger, DHHC-type containing 6 -2.22964
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.22554
CNN3 calponin 3, acidic -2.22543
CD58 CD58 molecule -2.21949
SNX10 sorting nexin 10 -2.21387
CAPN10 calpain 10 -2.21357
TMEM164 transmembrane protein 164 -2.21017
ZBTB24 zinc finger and BTB domain containing 24 -2.2099
KRT13 keratin 13, type I -2.20629
PRPF31 pre-mRNA processing factor 31 -2.20227
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.19474
MSH2 mutS homolog 2 -2.19249
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -2.18683
CDC23 cell division cycle 23 -2.18333
FANCI Fanconi anemia, complementation group I -2.17812
FAT2 FAT atypical cadherin 2 -2.17688
TEDC2 tubulin epsilon and delta complex 2 -2.17239
MDC1 mediator of DNA-damage checkpoint 1 -2.17235
FOXM1 forkhead box M1 -2.17104
ATL2 atlastin GTPase 2 -2.17014
CDC7 cell division cycle 7 -2.17009
SRSF7 serine/arginine-rich splicing factor 7 -2.16921
RGS19 regulator of G-protein signaling 19 -2.16918
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) -2.16636
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) -2.16543
MAP3K6 mitogen-activated protein kinase kinase kinase 6 -2.1643
THUMPD2 THUMP domain containing 2 -2.15883
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -2.15633
PLK1 polo-like kinase 1 -2.15518
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 -2.15192
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -2.14989
LHX1 LIM homeobox 1 -2.14857
DPYD dihydropyrimidine dehydrogenase -2.14852
MCMBP minichromosome maintenance complex binding protein -2.14812
GEMIN4 gem (nuclear organelle) associated protein 4 -2.14604
BTBD2 BTB (POZ) domain containing 2 -2.14044
LBR lamin B receptor -2.14012
MPC2 mitochondrial pyruvate carrier 2 -2.13951
PLAAT4 phospholipase A and acyltransferase 4 -2.1392
FHL5 four and a half LIM domains 5 -2.1368
HMG20B high mobility group 20B -2.13653
PGRMC1 progesterone receptor membrane component 1 -2.13389
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.13054
PHF2 PHD finger protein 2 -2.12752
PPP1R12B protein phosphatase 1, regulatory subunit 12B -2.12115
SRRT serrate, RNA effector molecule -2.11896
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -2.11831
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -2.11238
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta -2.11182
GTF2A2 general transcription factor IIA, 2, 12kDa -2.10994
DEF8 differentially expressed in FDCP 8 homolog (mouse) -2.10969
CENPA centromere protein A -2.10904
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -2.10267
ALG8 ALG8, alpha-1,3-glucosyltransferase -2.10253
MYH11 myosin, heavy chain 11, smooth muscle -2.10163
NASP nuclear autoantigenic sperm protein (histone-binding) -2.09455
APH1A APH1A gamma secretase subunit -2.09373
DBF4 DBF4 zinc finger -2.09237
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like -2.09004
PLSCR1 phospholipid scramblase 1 -2.08821
PNPLA3 patatin-like phospholipase domain containing 3 -2.0867
TMEM255A transmembrane protein 255A -2.086
SPTBN2 spectrin, beta, non-erythrocytic 2 -2.08413
RIPK4 receptor-interacting serine-threonine kinase 4 -2.08332
NEK2 NIMA-related kinase 2 -2.08154
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -2.08124
MVP major vault protein -2.07824
CORO1A coronin, actin binding protein, 1A -2.07414
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 -2.07392
CDC25A cell division cycle 25A -2.0711
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -2.06835
NUP107 nucleoporin 107kDa -2.06584
PHACTR1 phosphatase and actin regulator 1 -2.06252
KIF4A kinesin family member 4A -2.05629
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 -2.05583
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.05562
ARHGAP11A Rho GTPase activating protein 11A -2.05552
TRIP10 thyroid hormone receptor interactor 10 -2.05491
DDR1 discoidin domain receptor tyrosine kinase 1 -2.05383
KLHDC3 kelch domain containing 3 -2.05365
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.04936
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa -2.04677
PTTG1 pituitary tumor-transforming 1 -2.04423
MCM4 minichromosome maintenance complex component 4 -2.04328
PDGFRL platelet-derived growth factor receptor-like -2.04258
RUVBL2 RuvB-like AAA ATPase 2 -2.04244
JAG2 jagged 2 -2.04199
LARS2 leucyl-tRNA synthetase 2, mitochondrial -2.03877
CCN5 cellular communication network factor 5 -2.03836
MED22 mediator complex subunit 22 -2.03623
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.03609
FMO1 flavin containing monooxygenase 1 -2.03177
STEAP4 STEAP family member 4 -2.03086
DEPDC1 DEP domain containing 1 -2.02844
CCNB2 cyclin B2 -2.02799
SCD stearoyl-CoA desaturase (delta-9-desaturase) -2.0268
TROAP trophinin associated protein -2.02214
UBAP2L ubiquitin associated protein 2-like -2.02176
ASB6 ankyrin repeat and SOCS box containing 6 -2.0217
CSAG2 CSAG family, member 2 -2.02048
STARD7 StAR-related lipid transfer (START) domain containing 7 -2.01903
ZDHHC13 zinc finger, DHHC-type containing 13 -2.0181
HSPA1B heat shock 70kDa protein 1B -2.01798
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -2.01571
CLUH clustered mitochondria (cluA/CLU1) homolog -2.01537
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -2.01181