CRCGN017_MCF10A.TP53.M_24H:J15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:J15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NOTCH1 notch 1 3.27089
PPP1R13B protein phosphatase 1, regulatory subunit 13B 3.18269
SSBP2 single-stranded DNA binding protein 2 3.13306
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.07552
GFOD1 glucose-fructose oxidoreductase domain containing 1 3.0635
E2F2 E2F transcription factor 2 3.04212
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.64616
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.58965
RAB21 RAB21, member RAS oncogene family 2.53322
KDM5A lysine (K)-specific demethylase 5A 2.32404
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.30708
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.15525
NOSIP nitric oxide synthase interacting protein 2.13595
ALOX15 arachidonate 15-lipoxygenase 2.05084
EVL Enah/Vasp-like 2.00434

decreased expression

Symbol Name Standardized Value
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -4.44915
CHMP4B charged multivesicular body protein 4B -3.64639
TES testin LIM domain protein -3.34388
HEATR1 HEAT repeat containing 1 -3.1327
CRK v-crk avian sarcoma virus CT10 oncogene homolog -2.97937
ANXA2 annexin A2 -2.83365
HAT1 histone acetyltransferase 1 -2.36439
KRT14 keratin 14, type I -2.1026