CRCGN017_MCF10A.TP53.M_24H:J16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description p,p'-dichlorodiphenyl sulfone 100.8 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:J16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KLHL9 kelch-like family member 9 7.0843
SPAG4 sperm associated antigen 4 4.94075
DHRS2 dehydrogenase/reductase (SDR family) member 2 4.07047
HBA1 hemoglobin, alpha 1 3.40641
ADAM10 ADAM metallopeptidase domain 10 3.23242
CNRIP1 cannabinoid receptor interacting protein 1 2.41805
PCCA propionyl CoA carboxylase, alpha polypeptide 2.34135
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.17995
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 2.0815

decreased expression

Symbol Name Standardized Value
CIAPIN1 cytokine induced apoptosis inhibitor 1 -5.6551
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -4.8298
SCYL3 SCY1-like 3 (S. cerevisiae) -4.75647
PCNA proliferating cell nuclear antigen -4.66275
HAT1 histone acetyltransferase 1 -4.1595
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 -3.871
CLTB clathrin, light chain B -3.80277
HEATR1 HEAT repeat containing 1 -3.76482
COTL1 coactosin-like F-actin binding protein 1 -3.2026
TOR1A torsin family 1, member A (torsin A) -2.96022
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.23645
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 -2.102
MSMO1 methylsterol monooxygenase 1 -2.06025
MGLL monoglyceride lipase -2.033
MYNN myoneurin -2.0132
CRNN cornulin -2.0038