CRCGN017_MCF10A.TP53.M_24H:J17 Gene Set
Genes
57 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:J17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
4.70187
|
|
MYLK
|
myosin light chain kinase
|
4.647
|
|
ACTG2
|
actin, gamma 2, smooth muscle, enteric
|
3.76181
|
|
IDE
|
insulin-degrading enzyme
|
3.22434
|
|
CNN1
|
calponin 1, basic, smooth muscle
|
2.59326
|
|
TOMM34
|
translocase of outer mitochondrial membrane 34
|
2.51411
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
2.50639
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.43247
|
|
MOK
|
MOK protein kinase
|
2.41078
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.40169
|
|
AGR2
|
anterior gradient 2
|
2.31268
|
|
WIF1
|
WNT inhibitory factor 1
|
2.30006
|
|
ACTA2
|
actin, alpha 2, smooth muscle, aorta
|
2.20815
|
|
LYZ
|
lysozyme
|
2.18716
|
|
COL6A3
|
collagen, type VI, alpha 3
|
2.12452
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.12378
|
|
UNC119
|
unc-119 homolog (C. elegans)
|
2.09072
|
|
IGHMBP2
|
immunoglobulin mu binding protein 2
|
2.07875
|
|
MFAP4
|
microfibrillar-associated protein 4
|
2.07214
|
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
|
2.03289
|
|
ATP6V1F
|
ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F
|
2.02779
|
|
MICALL1
|
MICAL-like 1
|
2.01856
|
|
ACKR1
|
atypical chemokine receptor 1 (Duffy blood group)
|
2.01682
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PUF60
|
poly-U binding splicing factor 60KDa
|
-7.449
|
|
GOLT1B
|
golgi transport 1B
|
-5.04236
|
|
SCRIB
|
scribbled planar cell polarity protein
|
-4.83341
|
|
SCYL3
|
SCY1-like 3 (S. cerevisiae)
|
-4.06509
|
|
ZNF16
|
zinc finger protein 16
|
-3.83824
|
|
ZNF7
|
zinc finger protein 7
|
-3.58739
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-3.54441
|
|
ANXA2
|
annexin A2
|
-3.5018
|
|
ERC2
|
ELKS/RAB6-interacting/CAST family member 2
|
-3.47495
|
|
SLC52A2
|
solute carrier family 52 (riboflavin transporter), member 2
|
-2.84009
|
|
ZMYM2
|
zinc finger, MYM-type 2
|
-2.52227
|
|
ZNF250
|
zinc finger protein 250
|
-2.47846
|
|
GPAA1
|
glycosylphosphatidylinositol anchor attachment 1
|
-2.44702
|
|
THEM6
|
thioesterase superfamily member 6
|
-2.39667
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
-2.38095
|
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
-2.37234
|
|
TOR1A
|
torsin family 1, member A (torsin A)
|
-2.36592
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.33853
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.30605
|
|
CMAS
|
cytidine monophosphate N-acetylneuraminic acid synthetase
|
-2.30393
|
|
ZNF34
|
zinc finger protein 34
|
-2.27047
|
|
RECQL
|
RecQ helicase-like
|
-2.25865
|
|
ZNF365
|
zinc finger protein 365
|
-2.19385
|
|
PMM2
|
phosphomannomutase 2
|
-2.18403
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.13729
|
|
GRAMD2B
|
GRAM domain containing 2B
|
-2.12345
|
|
LNPEP
|
leucyl/cystinyl aminopeptidase
|
-2.11004
|
|
NUP85
|
nucleoporin 85kDa
|
-2.09478
|
|
STYK1
|
serine/threonine/tyrosine kinase 1
|
-2.08394
|
|
ETNK1
|
ethanolamine kinase 1
|
-2.04981
|
|
PLEC
|
plectin
|
-2.03105
|
|
RTL8C
|
retrotransposon Gag like 8C
|
-2.02922
|
|
CPSF1
|
cleavage and polyadenylation specific factor 1, 160kDa
|
-2.01788
|
|
CUZD1
|
CUB and zona pellucida-like domains 1
|
-2.00228
|
