CRCGN017_MCF10A.TP53.M_24H:J18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description p,p'-dichlorodiphenyl sulfone 11.2 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

13 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:J18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 3.61736
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 3.07317
ADAM10 ADAM metallopeptidase domain 10 2.52635
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.4994
RPL39L ribosomal protein L39-like 2.21696
MCUR1 mitochondrial calcium uniporter regulator 1 2.11737
FCHO1 FCH domain only 1 2.09856
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.02502

decreased expression

Symbol Name Standardized Value
CD44 CD44 molecule (Indian blood group) -3.95512
RGS2 regulator of G-protein signaling 2 -2.11556
TRIB3 tribbles pseudokinase 3 -2.07237
CANT1 calcium activated nucleotidase 1 -2.05418
HEATR1 HEAT repeat containing 1 -2.0308