CRCGN017_MCF10A.TP53.M_24H:J19 Gene Set
Genes
49 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:J19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
SPAG4
|
sperm associated antigen 4
|
5.43306
|
|
AGR2
|
anterior gradient 2
|
5.12199
|
|
CCDC92
|
coiled-coil domain containing 92
|
4.95317
|
|
WASF3
|
WAS protein family, member 3
|
4.56824
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
3.24839
|
|
MCOLN1
|
mucolipin 1
|
3.17749
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
3.07818
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
3.01345
|
|
NARS2
|
asparaginyl-tRNA synthetase 2, mitochondrial (putative)
|
2.94715
|
|
COMP
|
cartilage oligomeric matrix protein
|
2.768
|
|
NFATC3
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
|
2.75392
|
|
CLNS1A
|
chloride channel, nucleotide-sensitive, 1A
|
2.67535
|
|
SESN1
|
sestrin 1
|
2.46168
|
|
THAP12
|
THAP domain containing 12
|
2.42999
|
|
HBB
|
hemoglobin, beta
|
2.37044
|
|
AAMDC
|
adipogenesis associated, Mth938 domain containing
|
2.25265
|
|
SH3YL1
|
SH3 and SYLF domain containing 1
|
2.19624
|
|
NUTF2
|
nuclear transport factor 2
|
2.18828
|
|
OSTF1
|
osteoclast stimulating factor 1
|
2.11463
|
|
RSF1
|
remodeling and spacing factor 1
|
2.05022
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.02064
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
NUP85
|
nucleoporin 85kDa
|
-4.97254
|
|
TES
|
testin LIM domain protein
|
-4.85078
|
|
BASP1
|
brain abundant, membrane attached signal protein 1
|
-4.82308
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-4.36997
|
|
KRT14
|
keratin 14, type I
|
-3.55378
|
|
GDF15
|
growth differentiation factor 15
|
-3.42464
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.3387
|
|
MRPL58
|
mitochondrial ribosomal protein L58
|
-3.11937
|
|
MRPS7
|
mitochondrial ribosomal protein S7
|
-3.10932
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.96014
|
|
TBCB
|
tubulin folding cofactor B
|
-2.91763
|
|
SAP30BP
|
SAP30 binding protein
|
-2.91556
|
|
BID
|
BH3 interacting domain death agonist
|
-2.84467
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
-2.79223
|
|
KCTD2
|
potassium channel tetramerization domain containing 2
|
-2.77879
|
|
SUMO4
|
small ubiquitin-like modifier 4
|
-2.75602
|
|
GRB2
|
growth factor receptor-bound protein 2
|
-2.61883
|
|
ANKRD27
|
ankyrin repeat domain 27 (VPS9 domain)
|
-2.59815
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.52395
|
|
CDR2L
|
cerebellar degeneration-related protein 2-like
|
-2.45681
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.42699
|
|
JPT1
|
Jupiter microtubule associated homolog 1
|
-2.26439
|
|
GMEB2
|
glucocorticoid modulatory element binding protein 2
|
-2.21267
|
|
NAT9
|
N-acetyltransferase 9 (GCN5-related, putative)
|
-2.20624
|
|
AREL1
|
apoptosis resistant E3 ubiquitin protein ligase 1
|
-2.18681
|
|
CERS1
|
ceramide synthase 1
|
-2.1734
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-2.17178
|
|
LLGL2
|
lethal giant larvae homolog 2 (Drosophila)
|
-2.09474
|