CRCGN017_MCF10A.TP53.M_24H:J20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4-acetylaminobiphenyl 33.51 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

40 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:J20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
BTK Bruton agammaglobulinemia tyrosine kinase 7.49054
CCDC92 coiled-coil domain containing 92 4.56868
MOK MOK protein kinase 3.09881
FGFR4 fibroblast growth factor receptor 4 2.76146
ADAT1 adenosine deaminase, tRNA-specific 1 2.66923
FCHO1 FCH domain only 1 2.60306
MAGEA6 melanoma antigen family A6 2.59348
COMP cartilage oligomeric matrix protein 2.52507
LOC100533997 MAGEA10-MAGEA5 readthrough 2.5246
MAGEA12 melanoma antigen family A12 2.48671
TBXA2R thromboxane A2 receptor 2.4449
MAGEA2B melanoma antigen family A2B 2.27207
TMEM160 transmembrane protein 160 2.22833
AMPD2 adenosine monophosphate deaminase 2 2.20992
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.17992
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 2.15453
CSAG2 CSAG family, member 2 2.06221
HOXA10 homeobox A10 2.04245
PHACTR1 phosphatase and actin regulator 1 2.00966

decreased expression

Symbol Name Standardized Value
TRAPPC3 trafficking protein particle complex 3 -4.99422
TCTA T-cell leukemia translocation altered -4.98764
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -4.93872
HAT1 histone acetyltransferase 1 -4.86308
ADI1 acireductone dioxygenase 1 -4.65579
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -2.62176
MRPS15 mitochondrial ribosomal protein S15 -2.48808
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -2.38734
KRCC1 lysine-rich coiled-coil 1 -2.30414
ANXA2 annexin A2 -2.30336
CAB39 calcium binding protein 39 -2.30202
RNF146 ring finger protein 146 -2.29259
RBM15B RNA binding motif protein 15B -2.25851
LMO3 LIM domain only 3 (rhombotin-like 2) -2.21811
TRIM25 tripartite motif containing 25 -2.07354
CASP8AP2 caspase 8 associated protein 2 -2.0681
NGRN neugrin, neurite outgrowth associated -2.0623
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) -2.03751
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) -2.01674
MAVS mitochondrial antiviral signaling protein -2.00471
MEX3D mex-3 RNA binding family member D -2.00314