CRCGN017_MCF10A.TP53.M_24H:J23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description pregnenolone 34.72 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

14 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:J23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 3.97502
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 3.47573
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 3.07265
SNAP25 synaptosomal-associated protein, 25kDa 2.44132
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.36641
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.34728
MELK maternal embryonic leucine zipper kinase 2.11455

decreased expression

Symbol Name Standardized Value
MSMO1 methylsterol monooxygenase 1 -3.82154
HAT1 histone acetyltransferase 1 -3.01623
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.22258
SOAT2 sterol O-acyltransferase 2 -2.12382
GSTM3 glutathione S-transferase mu 3 (brain) -2.12001
CBR1 carbonyl reductase 1 -2.04983
ANKRD10 ankyrin repeat domain 10 -2.00827