| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | edaravone 33.43 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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44 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:K02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADAM10 | ADAM metallopeptidase domain 10 | 4.7983 |
| KDM5D | lysine (K)-specific demethylase 5D | 3.43235 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 2.9918 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 2.82162 |
| MMP1 | matrix metallopeptidase 1 | 2.76472 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 2.61035 |
| GRB10 | growth factor receptor-bound protein 10 | 2.59057 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 2.4292 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 2.38315 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 2.18335 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 2.1548 |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 2.14892 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 2.14525 |
| POMC | proopiomelanocortin | 2.13185 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 2.11382 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 2.07283 |
| PRDX4 | peroxiredoxin 4 | 2.0581 |
| REXO4 | REX4, RNA exonuclease 4 homolog (S. cerevisiae) | 2.0352 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UFM1 | ubiquitin-fold modifier 1 | -5.1278 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.9498 |
| COG2 | component of oligomeric golgi complex 2 | -4.7989 |
| CD44 | CD44 molecule (Indian blood group) | -4.79249 |
| VDAC1 | voltage-dependent anion channel 1 | -4.44172 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.4076 |
| BID | BH3 interacting domain death agonist | -3.77515 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -2.88845 |
| GRN | granulin | -2.51547 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit | -2.451 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | -2.4456 |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 | -2.36485 |
| SMC1A | structural maintenance of chromosomes 1A | -2.35525 |
| PROSER1 | proline and serine rich 1 | -2.3458 |
| PAMR1 | peptidase domain containing associated with muscle regeneration 1 | -2.3157 |
| WBP4 | WW domain binding protein 4 | -2.27138 |
| SYNGR3 | synaptogyrin 3 | -2.2425 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | -2.22125 |
| PUDP | pseudouridine 5'-phosphatase | -2.17125 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -2.15887 |
| SPAG7 | sperm associated antigen 7 | -2.15775 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -2.1093 |
| FBXO7 | F-box protein 7 | -2.1066 |
| KDM5C | lysine (K)-specific demethylase 5C | -2.0994 |
| LOC124905557 | eukaryotic translation initiation factor 1A, X-chromosomal | -2.09825 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.0288 |
