CRCGN017_MCF10A.TP53.M_24H:K04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description glutaraldehyde 96.8 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:K04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 7.83381
UBQLN2 ubiquilin 2 3.78243
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 3.7711
MAMLD1 mastermind-like domain containing 1 3.07269
KLHL9 kelch-like family member 9 2.97698
HLA-DRA major histocompatibility complex, class II, DR alpha 2.42019
HMOX1 heme oxygenase 1 2.27364
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.16885
RANBP6 RAN binding protein 6 2.1339
AGR2 anterior gradient 2 2.12365
CNRIP1 cannabinoid receptor interacting protein 1 2.03778
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.02794

decreased expression

Symbol Name Standardized Value
TNIP1 TNFAIP3 interacting protein 1 -4.24832
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.64727
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -3.51601
COTL1 coactosin-like F-actin binding protein 1 -3.45809
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.73981
NGRN neugrin, neurite outgrowth associated -2.44737
IGFBP7 insulin-like growth factor binding protein 7 -2.30558
PIH1D1 PIH1 domain containing 1 -2.29636
CD320 CD320 molecule -2.09648