CRCGN017_MCF10A.TP53.M_24H:K11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description wortmannin 3.33 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

444 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:K11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 6.77611
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 4.20839
CDC45 cell division cycle 45 4.04072
MAMLD1 mastermind-like domain containing 1 3.86956
ZMIZ1 zinc finger, MIZ-type containing 1 3.72308
PFKL phosphofructokinase, liver 3.66222
CXCL2 chemokine (C-X-C motif) ligand 2 3.65863
SMIM40 small integral membrane protein 40 3.39186
PWP2 PWP2 periodic tryptophan protein homolog (yeast) 3.15269
JAG2 jagged 2 3.12065
TRAPPC10 trafficking protein particle complex 10 3.06641
GRB7 growth factor receptor-bound protein 7 3.05627
SYNGR4 synaptogyrin 4 2.98601
CIC capicua transcriptional repressor 2.97023
SMG9 SMG9 nonsense mediated mRNA decay factor 2.93035
SPAG4 sperm associated antigen 4 2.92248
CPNE7 copine VII 2.87554
WDR7 WD repeat domain 7 2.85408
PACS2 phosphofurin acidic cluster sorting protein 2 2.82926
SCCPDH saccharopine dehydrogenase (putative) 2.82672
NOTCH1 notch 1 2.82507
MYL9 myosin, light chain 9, regulatory 2.81797
DPEP1 dipeptidase 1 (renal) 2.81366
TNIP1 TNFAIP3 interacting protein 1 2.81339
ZNF232 zinc finger protein 232 2.80817
FBXL6 F-box and leucine-rich repeat protein 6 2.78766
VAC14 Vac14 homolog (S. cerevisiae) 2.77853
TBC1D17 TBC1 domain family, member 17 2.73344
NUAK2 NUAK family, SNF1-like kinase, 2 2.7247
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 2.69573
LOC102723996 ICOS ligand 2.69106
ACVRL1 activin A receptor type II-like 1 2.68624
APOL3 apolipoprotein L, 3 2.68557
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 2.683
MED9 mediator complex subunit 9 2.68264
KCNK12 potassium channel, two pore domain subfamily K, member 12 2.66011
GATD3 glutamine amidotransferase class 1 domain containing 3 2.66
DGCR8 DGCR8 microprocessor complex subunit 2.64753
DOK3 docking protein 3 2.64277
MAP3K11 mitogen-activated protein kinase kinase kinase 11 2.63877
ZNF667 zinc finger protein 667 2.6366
THBS3 thrombospondin 3 2.62895
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 2.62268
CHN1 chimerin 1 2.62201
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.61216
CDK3 cyclin-dependent kinase 3 2.61196
TIMP2 TIMP metallopeptidase inhibitor 2 2.6113
CRELD2 cysteine-rich with EGF-like domains 2 2.60992
STARD5 StAR-related lipid transfer (START) domain containing 5 2.6023
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.59812
HYOU1 hypoxia up-regulated 1 2.59793
KEL Kell blood group, metallo-endopeptidase 2.59291
WNT1 wingless-type MMTV integration site family, member 1 2.59194
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 2.58592
LGALS4 lectin, galactoside-binding, soluble, 4 2.56605
PODXL2 podocalyxin-like 2 2.55636
ZNF180 zinc finger protein 180 2.55324
FKRP fukutin related protein 2.53095
RPAP2 RNA polymerase II associated protein 2 2.52171
ATOH1 atonal homolog 1 (Drosophila) 2.51321
RAB40C RAB40C, member RAS oncogene family 2.51036
RAB21 RAB21, member RAS oncogene family 2.50087
ZNF250 zinc finger protein 250 2.48755
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.47339
RENBP renin binding protein 2.46607
ZNF839 zinc finger protein 839 2.46119
ZNF692 zinc finger protein 692 2.45627
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 2.45276
HSF1 heat shock transcription factor 1 2.45157
TRIM46 tripartite motif containing 46 2.44862
DENND1B DENN/MADD domain containing 1B 2.44858
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) 2.43843
E2F1 E2F transcription factor 1 2.43485
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D 2.41717
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 2.40618
PCDHGA5 protocadherin gamma subfamily A, 5 2.39847
MMP12 matrix metallopeptidase 12 2.39509
RAI14 retinoic acid induced 14 2.3938
KDM8 lysine (K)-specific demethylase 8 2.39304
ECEL1 endothelin converting enzyme-like 1 2.39205
IFNAR1 interferon (alpha, beta and omega) receptor 1 2.3858
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa 2.38571
IL1B interleukin 1, beta 2.38541
PLXNB2 plexin B2 2.38396
H2AP H2A.P histone 2.38015
DOC2B double C2-like domains, beta 2.36881
EXOSC5 exosome component 5 2.36684
MUC2 mucin 2, oligomeric mucus/gel-forming 2.36346
TDRD12 tudor domain containing 12 2.36113
PPP1R13L protein phosphatase 1, regulatory subunit 13 like 2.3608
PCNT pericentrin 2.3594
BAMBI BMP and activin membrane-bound inhibitor 2.35697
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q 2.35575
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2.34877
IRF3 interferon regulatory factor 3 2.34814
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 2.34592
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.34544
DUSP21 dual specificity phosphatase 21 2.34203
EGF epidermal growth factor 2.33879
ARSA arylsulfatase A 2.33732
CDX1 caudal type homeobox 1 2.33549
IRF2BP1 interferon regulatory factor 2 binding protein 1 2.33324
SPIB Spi-B transcription factor (Spi-1/PU.1 related) 2.32817
FTCD formimidoyltransferase cyclodeaminase 2.32562
ARHGAP33 Rho GTPase activating protein 33 2.32235
IRF9 interferon regulatory factor 9 2.31671
ARHGAP8 Rho GTPase activating protein 8 2.31496
LRRK1 leucine-rich repeat kinase 1 2.31089
ALG12 ALG12, alpha-1,6-mannosyltransferase 2.30575
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 2.30474
HELLS helicase, lymphoid-specific 2.30394
LMF2 lipase maturation factor 2 2.29518
CXCL3 chemokine (C-X-C motif) ligand 3 2.28698
ZFYVE26 zinc finger, FYVE domain containing 26 2.28468
CDHR5 cadherin-related family member 5 2.28451
BCAM basal cell adhesion molecule (Lutheran blood group) 2.2839
THOP1 thimet oligopeptidase 1 2.28143
EXO1 exonuclease 1 2.27878
UBE2J1 ubiquitin-conjugating enzyme E2, J1 2.26844
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 2.26546
CLEC5A C-type lectin domain family 5, member A 2.26447
GSPT2 G1 to S phase transition 2 2.26
DRAM1 DNA-damage regulated autophagy modulator 1 2.25716
MMP17 matrix metallopeptidase 17 (membrane-inserted) 2.25684
FHIP2B FHF complex subunit HOOK interacting protein 2B 2.2567
IRF1 interferon regulatory factor 1 2.25637
GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 2.25097
UBQLN2 ubiquilin 2 2.24899
TRABD TraB domain containing 2.2471
HOXD3 homeobox D3 2.24443
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 2.24337
SLC7A4 solute carrier family 7, member 4 2.24323
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.24126
DIPK1A divergent protein kinase domain 1A 2.23912
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.2372
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 2.23015
DNAH2 dynein, axonemal, heavy chain 2 2.22902
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 2.22853
FOXC2 forkhead box C2 2.22839
GNG4 guanine nucleotide binding protein (G protein), gamma 4 2.22666
ZNF112 zinc finger protein 112 2.2265
CHKB choline kinase beta 2.22257
CHAF1A chromatin assembly factor 1, subunit A (p150) 2.22068
HAAO 3-hydroxyanthranilate 3,4-dioxygenase 2.22038
XDH xanthine dehydrogenase 2.21848
SH3BP1 SH3-domain binding protein 1 2.2177
CDT1 chromatin licensing and DNA replication factor 1 2.21742
IL15RA interleukin 15 receptor, alpha 2.2174
PALM paralemmin 2.21733
VIL1 villin 1 2.21575
SBF1 SET binding factor 1 2.21335
RBM41 RNA binding motif protein 41 2.21318
HOXB1 homeobox B1 2.20563
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 2.19294
SSTR2 somatostatin receptor 2 2.18988
DOT1L DOT1-like histone H3K79 methyltransferase 2.18777
ZKSCAN4 zinc finger with KRAB and SCAN domains 4 2.18666
PPOX protoporphyrinogen oxidase 2.1863
SOX18 SRY (sex determining region Y)-box 18 2.1849
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 2.18229
TMPRSS6 transmembrane protease, serine 6 2.18129
IVNS1ABP influenza virus NS1A binding protein 2.17919
FKBP8 FK506 binding protein 8, 38kDa 2.17912
EPHB1 EPH receptor B1 2.1781
ITFG1 integrin alpha FG-GAP repeat containing 1 2.17771
NGF nerve growth factor (beta polypeptide) 2.1764
CRTAC1 cartilage acidic protein 1 2.17484
ADM2 adrenomedullin 2 2.17193
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.17095
CCNE2 cyclin E2 2.16716
GUSB glucuronidase, beta 2.16598
VEGFB vascular endothelial growth factor B 2.16545
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase 2.16506
ATP2A3 ATPase, Ca++ transporting, ubiquitous 2.1645
CAMK1D calcium/calmodulin-dependent protein kinase ID 2.16342
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4 2.16164
AP4M1 adaptor-related protein complex 4, mu 1 subunit 2.16105
JADE3 jade family PHD finger 3 2.1532
CPA2 carboxypeptidase A2 (pancreatic) 2.15297
ACAA1 acetyl-CoA acyltransferase 1 2.14862
CD180 CD180 molecule 2.14595
RASL10A RAS-like, family 10, member A 2.14332
OVOL3 ovo-like zinc finger 3 2.14035
MAPK11 mitogen-activated protein kinase 11 2.14
CLPTM1 cleft lip and palate associated transmembrane protein 1 2.13845
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 2.13831
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 2.13715
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2.13612
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) 2.13449
RAD54L RAD54-like (S. cerevisiae) 2.13117
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 2.12625
GPR161 G protein-coupled receptor 161 2.12495
CA7 carbonic anhydrase VII 2.12441
NHEJ1 nonhomologous end-joining factor 1 2.12431
CISH cytokine inducible SH2-containing protein 2.1243
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 2.12374
ELAC1 elaC ribonuclease Z 1 2.12067
PCDHA9 protocadherin alpha 9 2.11736
MCM5 minichromosome maintenance complex component 5 2.11465
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13 2.11222
TPSG1 tryptase gamma 1 2.11218
OPN1MW3 opsin 1, medium wave sensitive 3 2.1112
ACTL7B actin-like 7B 2.10883
RHD Rh blood group, D antigen 2.1088
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 2.10877
ETV7 ets variant 7 2.10794
RBM8A RNA binding motif protein 8A 2.10736
RAB43 RAB43, member RAS oncogene family 2.10727
TBCEL tubulin folding cofactor E-like 2.10634
SF3A3 splicing factor 3a, subunit 3, 60kDa 2.10411
BMX BMX non-receptor tyrosine kinase 2.10238
CLEC16A C-type lectin domain family 16, member A 2.09274
INA internexin neuronal intermediate filament protein, alpha 2.09232
GRN granulin 2.09073
RCL1 RNA terminal phosphate cyclase-like 1 2.09073
PPP6R2 protein phosphatase 6, regulatory subunit 2 2.0902
RHCE Rh blood group, CcEe antigens 2.08978
FFAR3 free fatty acid receptor 3 2.08852
EFR3B EFR3 homolog B (S. cerevisiae) 2.08703
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 2.0864
ARL4C ADP-ribosylation factor-like 4C 2.08556
LOXL2 lysyl oxidase-like 2 2.08521
TP73 tumor protein p73 2.08256
MEGF6 multiple EGF-like-domains 6 2.08225
LIMD2 LIM domain containing 2 2.08175
TRPC7 transient receptor potential cation channel, subfamily C, member 7 2.08008
FANCA Fanconi anemia, complementation group A 2.07958
PLD3 phospholipase D family, member 3 2.07835
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 2.07735
KLF1 Kruppel-like factor 1 (erythroid) 2.07704
GPR50 G protein-coupled receptor 50 2.0768
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 2.07511
MOB3B MOB kinase activator 3B 2.07502
TBC1D31 TBC1 domain family, member 31 2.07494
RSPH6A radial spoke head 6 homolog A (Chlamydomonas) 2.07441
EPS8L3 EPS8-like 3 2.07429
ZNF548 zinc finger protein 548 2.07293
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae) 2.07174
TREH trehalase (brush-border membrane glycoprotein) 2.07002
RHAG Rh-associated glycoprotein 2.06986
NCF1 neutrophil cytosolic factor 1 2.06791
PMFBP1 polyamine modulated factor 1 binding protein 1 2.06597
BRCA1 breast cancer 1, early onset 2.06515
PLXNB1 plexin B1 2.06197
MAPK7 mitogen-activated protein kinase 7 2.06193
CX3CL1 chemokine (C-X3-C motif) ligand 1 2.06167
LRRC3 leucine rich repeat containing 3 2.06119
SARM1 sterile alpha and TIR motif containing 1 2.06052
GPA33 glycoprotein A33 (transmembrane) 2.05958
PAQR4 progestin and adipoQ receptor family member IV 2.05498
GJA9 gap junction protein, alpha 9, 59kDa 2.05477
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 2.05303
CSPP1 centrosome and spindle pole associated protein 1 2.05143
ZFP2 ZFP2 zinc finger protein 2.05102
EIF3CL eukaryotic translation initiation factor 3, subunit C-like 2.04983
IPO13 importin 13 2.04748
TMEM259 transmembrane protein 259 2.04414
AMELX amelogenin, X-linked 2.04406
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 2.04318
FRMPD1 FERM and PDZ domain containing 1 2.04121
PWWP3A PWWP domain containing 3A, DNA repair factor 2.03786
TERT telomerase reverse transcriptase 2.03736
CNOT3 CCR4-NOT transcription complex, subunit 3 2.03367
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6 2.03285
BCL3 B-cell CLL/lymphoma 3 2.03283
NTN3 netrin 3 2.03277
OSBP2 oxysterol binding protein 2 2.03163
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta 2.03073
PRKD2 protein kinase D2 2.03051
NHERF4 NHERF family PDZ scaffold protein 4 2.02843
GNRH2 gonadotropin-releasing hormone 2 2.02506
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 2.02452
TMEM176A transmembrane protein 176A 2.02131
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 2.02018
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 2.01947
ZBTB48 zinc finger and BTB domain containing 48 2.01896
LIMK2 LIM domain kinase 2 2.01773
SCIN scinderin 2.01129
TCF3 transcription factor 3 2.01123
PCSK7 proprotein convertase subtilisin/kexin type 7 2.00763
CLIC2 chloride intracellular channel 2 2.00649
CLCNKB chloride channel, voltage-sensitive Kb 2.00474
UCMA upper zone of growth plate and cartilage matrix associated 2.00438
ZFP36L2 ZFP36 ring finger protein-like 2 2.00395
POU3F3 POU class 3 homeobox 3 2.00351
GPR137 G protein-coupled receptor 137 2.00318
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 2.0028

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -5.03547
CDK7 cyclin-dependent kinase 7 -4.26189
CHIC2 cysteine-rich hydrophobic domain 2 -4.16473
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -4.16345
CDC20 cell division cycle 20 -4.0359
ENOPH1 enolase-phosphatase 1 -3.91195
CCNB2 cyclin B2 -3.84977
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -3.60622
RPA3 replication protein A3, 14kDa -3.57913
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -3.53547
CYCS cytochrome c, somatic -3.46829
ANXA2 annexin A2 -3.38961
CGRRF1 cell growth regulator with ring finger domain 1 -3.21076
GTF2A2 general transcription factor IIA, 2, 12kDa -3.16228
SLC35B1 solute carrier family 35, member B1 -3.15607
MNAT1 MNAT CDK-activating kinase assembly factor 1 -3.13306
ECD ecdysoneless homolog (Drosophila) -2.99117
PCCB propionyl CoA carboxylase, beta polypeptide -2.98823
KIF20A kinesin family member 20A -2.91974
ZNHIT3 zinc finger, HIT-type containing 3 -2.90988
COPS4 COP9 signalosome subunit 4 -2.89317
DDIT4 DNA-damage-inducible transcript 4 -2.88949
KIF14 kinesin family member 14 -2.85317
TMEM126B transmembrane protein 126B -2.845
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -2.80959
RPL39L ribosomal protein L39-like -2.78951
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -2.78823
PCDHB16 protocadherin beta 16 -2.75688
LBR lamin B receptor -2.75095
INPP1 inositol polyphosphate-1-phosphatase -2.70859
MRPL12 mitochondrial ribosomal protein L12 -2.66561
ANKRD10 ankyrin repeat domain 10 -2.65736
FIP1L1 factor interacting with PAPOLA and CPSF1 -2.65647
COXFA4 cytochrome c oxidase associated subunit FA4 -2.6455
PARL presenilin associated, rhomboid-like -2.64131
HIGD1A HIG1 hypoxia inducible domain family, member 1A -2.63053
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -2.62115
FAM131A family with sequence similarity 131, member A -2.61699
AARS1 alanyl-tRNA synthetase 1 -2.61046
UBE2K ubiquitin-conjugating enzyme E2K -2.59516
RBM7 RNA binding motif protein 7 -2.59205
CCNA2 cyclin A2 -2.58639
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 -2.58467
ANXA7 annexin A7 -2.5787
ARFIP2 ADP-ribosylation factor interacting protein 2 -2.56127
SAR1B secretion associated, Ras related GTPase 1B -2.55645
PSRC1 proline/serine-rich coiled-coil 1 -2.55511
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.52503
SRFBP1 serum response factor binding protein 1 -2.51901
MFN1 mitofusin 1 -2.51049
ITCH itchy E3 ubiquitin protein ligase -2.50325
RAB5IF RAB5 interacting factor -2.49718
BHLHE40 basic helix-loop-helix family, member e40 -2.47129
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.46322
KDM3A lysine (K)-specific demethylase 3A -2.45074
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa -2.44792
BAG2 BCL2-associated athanogene 2 -2.44792
MRPS22 mitochondrial ribosomal protein S22 -2.44238
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -2.43679
NLRP2B NLR family pyrin domain containing 2B -2.43414
RPL26L1 ribosomal protein L26-like 1 -2.4325
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase -2.42702
DENR density-regulated protein -2.42597
MKRN2 makorin ring finger protein 2 -2.41459
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.41448
PRPF18 pre-mRNA processing factor 18 -2.41073
TARS1 threonyl-tRNA synthetase 1 -2.40432
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 -2.4035
PELO pelota homolog (Drosophila) -2.40271
PGM1 phosphoglucomutase 1 -2.39932
NPR2 natriuretic peptide receptor 2 -2.39147
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) -2.3607
ARPC5L actin related protein 2/3 complex, subunit 5-like -2.35348
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 -2.35276
ACTR6 ARP6 actin-related protein 6 homolog (yeast) -2.35151
PCNP PEST proteolytic signal containing nuclear protein -2.34915
GOLT1B golgi transport 1B -2.34595
RHOT1 ras homolog family member T1 -2.33971
GLRX glutaredoxin (thioltransferase) -2.33804
TXNDC9 thioredoxin domain containing 9 -2.32999
ADI1 acireductone dioxygenase 1 -2.32857
MED21 mediator complex subunit 21 -2.3256
CLTC clathrin, heavy chain (Hc) -2.3243
MED4 mediator complex subunit 4 -2.32245
MSL2 male-specific lethal 2 homolog (Drosophila) -2.3223
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -2.31617
PTS 6-pyruvoyltetrahydropterin synthase -2.30002
CTR9 CTR9, Paf1/RNA polymerase II complex component -2.29786
MRPL42 mitochondrial ribosomal protein L42 -2.28673
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 -2.27827
CPVL carboxypeptidase, vitellogenic-like -2.26615
DNM1L dynamin 1-like -2.26533
COX7B cytochrome c oxidase subunit VIIb -2.2607
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -2.24692
TEFM transcription elongation factor, mitochondrial -2.24277
SRPRB signal recognition particle receptor, B subunit -2.23961
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.21563
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -2.20987
PHGDH phosphoglycerate dehydrogenase -2.20652
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 -2.20145
CKAP5 cytoskeleton associated protein 5 -2.19908
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa -2.19846
SLC35F2 solute carrier family 35, member F2 -2.19042
TRIAP1 TP53 regulated inhibitor of apoptosis 1 -2.18219
OXSM 3-oxoacyl-ACP synthase, mitochondrial -2.1739
ATP5F1A ATP synthase F1 subunit alpha -2.17322
PPIC peptidylprolyl isomerase C (cyclophilin C) -2.16895
VDAC3 voltage-dependent anion channel 3 -2.16375
ANO10 anoctamin 10 -2.16307
SESN1 sestrin 1 -2.16297
ASNS asparagine synthetase (glutamine-hydrolyzing) -2.15811
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit -2.15412
VAMP7 vesicle-associated membrane protein 7 -2.15127
PPARG peroxisome proliferator-activated receptor gamma -2.14875
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase -2.14755
UBP1 upstream binding protein 1 (LBP-1a) -2.14411
CBR3 carbonyl reductase 3 -2.14215
DUSP14 dual specificity phosphatase 14 -2.1381
CMC2 C-x(9)-C motif containing 2 -2.13383
DIABLO diablo, IAP-binding mitochondrial protein -2.13157
MRPL58 mitochondrial ribosomal protein L58 -2.12266
ANKRD17 ankyrin repeat domain 17 -2.12181
ANXA5 annexin A5 -2.11912
GOLGA7 golgin A7 -2.11693
BMPR1A bone morphogenetic protein receptor, type IA -2.11552
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa -2.11386
ZMYM2 zinc finger, MYM-type 2 -2.11331
ISOC1 isochorismatase domain containing 1 -2.10107
SKP1 S-phase kinase-associated protein 1 -2.0991
ADNP activity-dependent neuroprotector homeobox -2.09575
BZW1 basic leucine zipper and W2 domains 1 -2.09468
RAB11A RAB11A, member RAS oncogene family -2.08928
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.08825
ASCC1 activating signal cointegrator 1 complex subunit 1 -2.08782
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 -2.08217
PUM2 pumilio RNA-binding family member 2 -2.0735
NCOA6 nuclear receptor coactivator 6 -2.07226
MDH1 malate dehydrogenase 1, NAD (soluble) -2.06718
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 -2.06639
PFDN2 prefoldin subunit 2 -2.06349
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa -2.06331
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -2.06028
MRPL49 mitochondrial ribosomal protein L49 -2.05975
MRPL35 mitochondrial ribosomal protein L35 -2.05835
CST3 cystatin C -2.05835
UBL5 ubiquitin-like 5 -2.05711
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa -2.04915
INSIG1 insulin induced gene 1 -2.03772
TMED1 transmembrane emp24 protein transport domain containing 1 -2.03669
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase -2.03184
KIN Kin17 DNA and RNA binding protein -2.02787
KRT10 keratin 10, type I -2.0231
BLTP3B bridge-like lipid transfer protein family member 3B -2.01897
COPS5 COP9 signalosome subunit 5 -2.0147
TOP2B topoisomerase (DNA) II beta 180kDa -2.01361
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.01022
COMMD10 COMM domain containing 10 -2.00097