CRCGN017_MCF10A.TP53.M_24H:K13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acrylamide 100.3 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

13 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:K13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FGFR4 fibroblast growth factor receptor 4 4.37189
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 3.25207
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) 3.03146
EPHB2 EPH receptor B2 2.26072
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.16289
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.07259

decreased expression

Symbol Name Standardized Value
CHMP4B charged multivesicular body protein 4B -4.68683
RNF167 ring finger protein 167 -4.48188
PCNA proliferating cell nuclear antigen -3.23877
GDF15 growth differentiation factor 15 -3.02099
CANT1 calcium activated nucleotidase 1 -2.58721
FHL2 four and a half LIM domains 2 -2.49809
TRIB3 tribbles pseudokinase 3 -2.33338