CRCGN017_MCF10A.TP53.M_24H:K15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acrylamide 11.14 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

18 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:K15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 5.10889
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 4.86254
MAP7 microtubule-associated protein 7 4.7375
WFS1 Wolfram syndrome 1 (wolframin) 4.55876
KLHL21 kelch-like family member 21 4.54767
ADGRE5 adhesion G protein-coupled receptor E5 2.24898
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 2.2391
BAMBI BMP and activin membrane-bound inhibitor 2.19164
HBB hemoglobin, beta 2.17326
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.15452
PPARG peroxisome proliferator-activated receptor gamma 2.13872

decreased expression

Symbol Name Standardized Value
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.92531
HAT1 histone acetyltransferase 1 -2.84904
GDF15 growth differentiation factor 15 -2.81173
TRIB3 tribbles pseudokinase 3 -2.59903
HMG20B high mobility group 20B -2.55487
MEST mesoderm specific transcript -2.37819
THAP11 THAP domain containing 11 -2.2491