CRCGN017_MCF10A.TP53.M_24H:K16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-aminoanthracene 101.3 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:K16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCL2 chemokine (C-C motif) ligand 2 3.45157
AXIN1 axin 1 3.38326
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 3.36033
SPAG4 sperm associated antigen 4 3.32977
CNRIP1 cannabinoid receptor interacting protein 1 2.88467
TLR4 toll-like receptor 4 2.86981
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2.77808
MAST2 microtubule associated serine/threonine kinase 2 2.37738
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 2.24241
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.1678

decreased expression

Symbol Name Standardized Value
UFM1 ubiquitin-fold modifier 1 -3.93647
DIPK1A divergent protein kinase domain 1A -3.71961
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.61913
RPIA ribose 5-phosphate isomerase A -3.59902
FOS FBJ murine osteosarcoma viral oncogene homolog -3.14602
HAT1 histone acetyltransferase 1 -3.11719
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -2.86697
DHRS7 dehydrogenase/reductase (SDR family) member 7 -2.69674
PUF60 poly-U binding splicing factor 60KDa -2.27748
TRAPPC3 trafficking protein particle complex 3 -2.23313
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K -2.1115
CD320 CD320 molecule -2.03439
TUBA4A tubulin, alpha 4a -2.02867