CRCGN017_MCF10A.TP53.M_24H:L02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description o-nitrotoluene 33.6 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:L02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 4.79825
E2F2 E2F transcription factor 2 4.66275
ACLY ATP citrate lyase 2.65147
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.64075
MUC1 mucin 1, cell surface associated 2.49422
CTSW cathepsin W 2.48235
SSX5 synovial sarcoma, X breakpoint 5 2.3661
REG1A regenerating islet-derived 1 alpha 2.35745
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 2.2981
CPAP centrosome assembly and centriole elongation protein 2.1661
DENND2D DENN/MADD domain containing 2D 2.15685
RBM3 RNA binding motif (RNP1, RRM) protein 3 2.09538
GDF9 growth differentiation factor 9 2.0918
SMG6 SMG6 nonsense mediated mRNA decay factor 2.07985
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.0304

decreased expression

Symbol Name Standardized Value
THAP11 THAP domain containing 11 -6.82425
TEX10 testis expressed 10 -5.46945
ACOT9 acyl-CoA thioesterase 9 -5.1177
GDF15 growth differentiation factor 15 -3.0101
CBR1 carbonyl reductase 1 -2.89495
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.3058
EXOSC4 exosome component 4 -2.22782
TRIB3 tribbles pseudokinase 3 -2.1282
COPZ2 coatomer protein complex, subunit zeta 2 -2.0345