CRCGN017_MCF10A.TP53.M_24H:L03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description o-nitrotoluene 11.2 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:L03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 4.66213
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 3.53878
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 3.40105
HBB hemoglobin, beta 3.29831
EPN2 epsin 2 2.8227
HYOU1 hypoxia up-regulated 1 2.49751
MMP1 matrix metallopeptidase 1 2.47669
GSTZ1 glutathione S-transferase zeta 1 2.38317
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 2.28868
HBA1 hemoglobin, alpha 1 2.27198
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 2.19731
MMP10 matrix metallopeptidase 10 2.11873
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 2.07053
MMP7 matrix metallopeptidase 7 2.05058
ZNF638 zinc finger protein 638 2.03959
PHACTR4 phosphatase and actin regulator 4 2.01241

decreased expression

Symbol Name Standardized Value
GOLT1B golgi transport 1B -4.96478
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -4.73506
COTL1 coactosin-like F-actin binding protein 1 -4.12191
CTNND1 catenin (cadherin-associated protein), delta 1 -4.02869
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -2.98564
TMX2 thioredoxin-related transmembrane protein 2 -2.76715
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 -2.71793
EIF5 eukaryotic translation initiation factor 5 -2.65373
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -2.35653
CNIH3 cornichon family AMPA receptor auxiliary protein 3 -2.23943
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) -2.17264
RECQL RecQ helicase-like -2.15671
BAD BCL2-associated agonist of cell death -2.1285