CRCGN017_MCF10A.TP53.M_24H:L05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description bromoethane 33.6 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:L05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 5.36435
ACAA1 acetyl-CoA acyltransferase 1 3.49716
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.90568
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.56003
KCTD5 potassium channel tetramerization domain containing 5 2.31335
MEF2C myocyte enhancer factor 2C 2.28678
SKIC8 SKI8 subunit of superkiller complex 2.25618
PRKCD protein kinase C, delta 2.19225
CIAO3 cytosolic iron-sulfur assembly component 3 2.11467
CERK ceramide kinase 2.02566

decreased expression

Symbol Name Standardized Value
TUBB6 tubulin, beta 6 class V -7.13474
KRT14 keratin 14, type I -5.0
THAP11 THAP domain containing 11 -3.64167
MAPK13 mitogen-activated protein kinase 13 -3.16089
CGRRF1 cell growth regulator with ring finger domain 1 -3.07724
HTRA1 HtrA serine peptidase 1 -2.35776
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -2.12617
PRELID3A PRELI domain containing 3A -2.02448
BASP1 brain abundant, membrane attached signal protein 1 -2.00769