CRCGN017_MCF10A.TP53.M_24H:L06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description bromoethane 11.2 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

36 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:L06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NGRN neugrin, neurite outgrowth associated 5.70435
CCL2 chemokine (C-C motif) ligand 2 5.4554
TBC1D31 TBC1 domain family, member 31 4.16775
CCP110 centriolar coiled coil protein 110kDa 4.16671
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.90923
RAB21 RAB21, member RAS oncogene family 2.89314
GRB10 growth factor receptor-bound protein 10 2.78221
ACAA1 acetyl-CoA acyltransferase 1 2.72164
TPD52L2 tumor protein D52-like 2 2.48011
EDN1 endothelin 1 2.42436
RNFT1-DT RNFT1 divergent transcript 2.22877
LY75-CD302 LY75-CD302 readthrough 2.21786
FOS FBJ murine osteosarcoma viral oncogene homolog 2.19779
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.17689
CGRRF1 cell growth regulator with ring finger domain 1 2.15909
BIRC3 baculoviral IAP repeat containing 3 2.10513
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.08201
THAP10 THAP domain containing 10 2.0665
UGDH UDP-glucose 6-dehydrogenase 2.05607
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 2.02869
HIRA histone cell cycle regulator 2.02406
ZNF273 zinc finger protein 273 2.0202
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) 2.01571

decreased expression

Symbol Name Standardized Value
KIF14 kinesin family member 14 -5.22657
COG2 component of oligomeric golgi complex 2 -4.3969
ELAC2 elaC ribonuclease Z 2 -2.96876
HEATR1 HEAT repeat containing 1 -2.9089
OXCT1 3-oxoacid CoA transferase 1 -2.5536
IFRD2 interferon-related developmental regulator 2 -2.36168
PSRC1 proline/serine-rich coiled-coil 1 -2.24609
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.2053
FER fer (fps/fes related) tyrosine kinase -2.11365
CTSL cathepsin L -2.11165
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -2.10429
MSX1 msh homeobox 1 -2.08851
FAM114A2 family with sequence similarity 114, member A2 -2.05058