CRCGN017_MCF10A.TP53.M_24H:L07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acrylonitrile 114.27 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:L07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCR4 chemokine (C-X-C motif) receptor 4 4.95283
ACAA1 acetyl-CoA acyltransferase 1 3.47259
MICALL1 MICAL-like 1 3.42911
CADM1 cell adhesion molecule 1 2.81887
IGHMBP2 immunoglobulin mu binding protein 2 2.73087
HBA1 hemoglobin, alpha 1 2.72425
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 2.58557
CARMIL1 capping protein regulator and myosin 1 linker 1 2.40974
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.18312
ZNF467 zinc finger protein 467 2.07269
CIAO3 cytosolic iron-sulfur assembly component 3 2.0541

decreased expression

Symbol Name Standardized Value
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -5.18347
PCNA proliferating cell nuclear antigen -4.77152
CCDC86 coiled-coil domain containing 86 -4.54294
THAP11 THAP domain containing 11 -4.41049
PSIP1 PC4 and SFRS1 interacting protein 1 -4.17757
DIPK1A divergent protein kinase domain 1A -3.94751
BASP1 brain abundant, membrane attached signal protein 1 -3.37127
NGRN neugrin, neurite outgrowth associated -3.10025
OXA1L oxidase (cytochrome c) assembly 1-like -2.94025
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -2.46156
OXCT1 3-oxoacid CoA transferase 1 -2.05363
RANBP6 RAN binding protein 6 -2.01543