CRCGN017_MCF10A.TP53.M_24H:L08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acrylonitrile 38.09 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:L08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
UBQLN2 ubiquilin 2 4.9082
ADAM10 ADAM metallopeptidase domain 10 4.41373
AGR2 anterior gradient 2 3.61795
HBA1 hemoglobin, alpha 1 3.14248
SATB1 SATB homeobox 1 2.7726
GRB10 growth factor receptor-bound protein 10 2.57443
TCTN2 tectonic family member 2 2.49945
GSTZ1 glutathione S-transferase zeta 1 2.1268
ZNF835 zinc finger protein 835 2.1242
PECR peroxisomal trans-2-enoyl-CoA reductase 2.09025
TECR trans-2,3-enoyl-CoA reductase 2.0175
ZNF528 zinc finger protein 528 2.00705

decreased expression

Symbol Name Standardized Value
AKT1 v-akt murine thymoma viral oncogene homolog 1 -6.1188
HSPA8 heat shock 70kDa protein 8 -5.33687
COG7 component of oligomeric golgi complex 7 -5.30655
YME1L1 YME1-like 1 ATPase -5.11537
ATG3 autophagy related 3 -2.852
ATF5 activating transcription factor 5 -2.50105
WAC WW domain containing adaptor with coiled-coil -2.45827
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) -2.348
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa -2.31717
NGRN neugrin, neurite outgrowth associated -2.2723
SCNN1B sodium channel, non voltage gated 1 beta subunit -2.244
BASP1 brain abundant, membrane attached signal protein 1 -2.1902
GDI2 GDP dissociation inhibitor 2 -2.0809