CRCGN017_MCF10A.TP53.M_24H:L10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description isoprene 99.8 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

27 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:L10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 4.94409
CXCR4 chemokine (C-X-C motif) receptor 4 3.74493
BDH1 3-hydroxybutyrate dehydrogenase, type 1 3.57097
MAST2 microtubule associated serine/threonine kinase 2 3.42962
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 3.13959
ZNF318 zinc finger protein 318 2.93073
CCNA1 cyclin A1 2.68501
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.64647
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 2.63924
TERT telomerase reverse transcriptase 2.47861
TXNL4B thioredoxin-like 4B 2.42373
GSTZ1 glutathione S-transferase zeta 1 2.17958
CRELD2 cysteine-rich with EGF-like domains 2 2.1104

decreased expression

Symbol Name Standardized Value
HAT1 histone acetyltransferase 1 -4.71594
VAT1 vesicle amine transport 1 -4.54907
PGAM4 phosphoglycerate mutase family member 4 -4.41788
NT5DC2 5'-nucleotidase domain containing 2 -3.83919
KRT14 keratin 14, type I -3.36902
ATF5 activating transcription factor 5 -3.10553
GDF15 growth differentiation factor 15 -2.7846
AP3S1 adaptor-related protein complex 3, sigma 1 subunit -2.36584
BACE2 beta-site APP-cleaving enzyme 2 -2.29769
SMAD7 SMAD family member 7 -2.22642
REEP5 receptor accessory protein 5 -2.21828
PORCN porcupine homolog (Drosophila) -2.1494
TM9SF2 transmembrane 9 superfamily member 2 -2.06376
RUNDC3B RUN domain containing 3B -2.05023