CRCGN017_MCF10A.TP53.M_24H:L11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description isoprene 33.27 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:L11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 5.0639
SPAG4 sperm associated antigen 4 4.54781
TBX2 T-box 2 4.14919
HBA1 hemoglobin, alpha 1 4.06208
ACAA1 acetyl-CoA acyltransferase 1 3.38282
KDM5A lysine (K)-specific demethylase 5A 3.00784
HBB hemoglobin, beta 2.98716
FOS FBJ murine osteosarcoma viral oncogene homolog 2.88515
ITGA7 integrin, alpha 7 2.14472
DHDDS dehydrodolichyl diphosphate synthase 2.07832
CCL19 chemokine (C-C motif) ligand 19 2.04191
FN3KRP fructosamine 3 kinase related protein 2.02084
CD2 CD2 molecule 2.00042

decreased expression

Symbol Name Standardized Value
WASHC4 WASH complex subunit 4 -5.2041
HSPA8 heat shock 70kDa protein 8 -4.72546
ENOPH1 enolase-phosphatase 1 -4.52942
TRIB3 tribbles pseudokinase 3 -2.98457
KRT14 keratin 14, type I -2.82712
HTRA1 HtrA serine peptidase 1 -2.29175
PSIP1 PC4 and SFRS1 interacting protein 1 -2.14906
MED17 mediator complex subunit 17 -2.13747
FASN fatty acid synthase -2.12032
DLK1 delta-like 1 homolog (Drosophila) -2.11397
ACTR6 ARP6 actin-related protein 6 homolog (yeast) -2.01535