CRCGN017_MCF10A.TP53.M_24H:L12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description isoprene 11.09 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

54 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:L12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 4.70192
STIMATE STIM activating enhancer 4.67068
SPAG4 sperm associated antigen 4 4.46384
CCP110 centriolar coiled coil protein 110kDa 4.42221
CASP2 caspase 2, apoptosis-related cysteine peptidase 4.38215
KIF5C kinesin family member 5C 4.11339
CNRIP1 cannabinoid receptor interacting protein 1 4.07206
COMP cartilage oligomeric matrix protein 3.84272
EPHA1 EPH receptor A1 2.99754
APEH acylaminoacyl-peptide hydrolase 2.55218
TIAM1 T-cell lymphoma invasion and metastasis 1 2.45347
B3GAT1 beta-1,3-glucuronyltransferase 1 2.39098
APOL3 apolipoprotein L, 3 2.33322
CXADR coxsackie virus and adenovirus receptor 2.24993
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.16364
SCARA3 scavenger receptor class A, member 3 2.13874
PRKCD protein kinase C, delta 2.13456
DENND2D DENN/MADD domain containing 2D 2.10572
CYB561D2 cytochrome b561 family, member D2 2.07429
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2 2.0555
EVPL envoplakin 2.03377
PYCARD PYD and CARD domain containing 2.02721
CFAP298 cilia and flagella associated protein 298 2.02402

decreased expression

Symbol Name Standardized Value
BAG3 BCL2-associated athanogene 3 -5.18848
BASP1 brain abundant, membrane attached signal protein 1 -4.48009
HMG20B high mobility group 20B -4.45736
COG2 component of oligomeric golgi complex 2 -4.26256
VDAC1 voltage-dependent anion channel 1 -4.19887
NPDC1 neural proliferation, differentiation and control, 1 -4.19648
GNAS GNAS complex locus -4.12685
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 -2.66992
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.51671
PABPC1 poly(A) binding protein, cytoplasmic 1 -2.46975
ATP11B ATPase, class VI, type 11B -2.42138
PHF20L1 PHD finger protein 20-like 1 -2.35214
EEF2 eukaryotic translation elongation factor 2 -2.32734
PRELID3B PRELI domain containing 3B -2.3075
WNT10B wingless-type MMTV integration site family, member 10B -2.19317
ZNF556 zinc finger protein 556 -2.18009
NOX5 NADPH oxidase, EF-hand calcium binding domain 5 -2.16555
ARFIP2 ADP-ribosylation factor interacting protein 2 -2.14806
CRTAP cartilage associated protein -2.12748
CD99 CD99 molecule -2.11093
NAXD NAD(P)HX dehydratase -2.11033
RPN2 ribophorin II -2.11012
PRDX5 peroxiredoxin 5 -2.09372
RPL19 ribosomal protein L19 -2.06712
RPL6 ribosomal protein L6 -2.05774
CENPC centromere protein C -2.04727
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa -2.03352
AHCTF1 AT hook containing transcription factor 1 -2.02655
ZBTB10 zinc finger and BTB domain containing 10 -2.02586
NELFCD negative elongation factor complex member C/D -2.00322
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit -2.00236