CRCGN017_MCF10A.TP53.M_24H:L14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-nitropropane 32.93 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

34 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:L14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 3.91692
ANO10 anoctamin 10 3.58745
CCDC92 coiled-coil domain containing 92 3.46432
AGR2 anterior gradient 2 3.43291
TATDN2 TatD DNase domain containing 2 3.41384
XPC xeroderma pigmentosum, complementation group C 3.35253
CXCR4 chemokine (C-X-C motif) receptor 4 3.33295
STK10 serine/threonine kinase 10 3.25958
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.72259
EMC3 ER membrane protein complex subunit 3 2.58913
CAPN7 calpain 7 2.55399
SEC13 SEC13 homolog (S. cerevisiae) 2.3638
IRAK4 interleukin-1 receptor-associated kinase 4 2.20413
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.18912
SLC41A3 solute carrier family 41, member 3 2.10789
SETD5 SET domain containing 5 2.06524
DYNLT1 dynein, light chain, Tctex-type 1 2.05759
GLB1 galactosidase, beta 1 2.02949

decreased expression

Symbol Name Standardized Value
MSMO1 methylsterol monooxygenase 1 -3.57534
GOLT1B golgi transport 1B -3.45982
SLC35F2 solute carrier family 35, member F2 -3.41356
CCNB1 cyclin B1 -3.40303
CTNND1 catenin (cadherin-associated protein), delta 1 -3.13658
PGAM4 phosphoglycerate mutase family member 4 -3.08562
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.63069
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.31935
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.3152
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.26792
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 -2.14646
PARG poly (ADP-ribose) glycohydrolase -2.13709
GATA6 GATA binding protein 6 -2.10412
LTC4S leukotriene C4 synthase -2.07113
PCDH8 protocadherin 8 -2.03594
NR2E1 nuclear receptor subfamily 2, group E, member 1 -2.01487