CRCGN017_MCF10A.TP53.M_24H:L15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-nitropropane 10.98 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:L15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGR2 anterior gradient 2 5.89698
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 4.73827
CXCR4 chemokine (C-X-C motif) receptor 4 4.64437
TBX2 T-box 2 3.77767
E2F2 E2F transcription factor 2 3.4141
TSPAN6 tetraspanin 6 2.88567
IGFBP3 insulin-like growth factor binding protein 3 2.60243
CENPE centromere protein E, 312kDa 2.2909

decreased expression

Symbol Name Standardized Value
PGAM4 phosphoglycerate mutase family member 4 -5.00823
ACOT9 acyl-CoA thioesterase 9 -5.00066
KRT14 keratin 14, type I -3.33499
HMG20B high mobility group 20B -3.21937
MSN moesin -2.86587
LYPLA1 lysophospholipase I -2.81822
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough -2.48114
CLTB clathrin, light chain B -2.45828
VASP vasodilator-stimulated phosphoprotein -2.42543
PSIP1 PC4 and SFRS1 interacting protein 1 -2.38296
RHOC ras homolog family member C -2.26011
HSPA1A heat shock 70kDa protein 1A -2.12386
PABPC1 poly(A) binding protein, cytoplasmic 1 -2.02687
NAP1L3 nucleosome assembly protein 1-like 3 -2.02024