CRCGN017_MCF10A.TP53.M_24H:L16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description ethyl methanesulfonate 101.3 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:L16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
E2F2 E2F transcription factor 2 5.47838
SCRN1 secernin 1 4.75751
SNAP25 synaptosomal-associated protein, 25kDa 4.73442
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 4.52872
STK10 serine/threonine kinase 10 4.46469
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 3.32877
RBP4 retinol binding protein 4, plasma 3.08357
USP6NL USP6 N-terminal like 2.98508
SQOR sulfide quinone oxidoreductase 2.83901
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 2.59678
STMN2 stathmin 2 2.28007
CTDNEP1 CTD nuclear envelope phosphatase 1 2.20579
SATB1 SATB homeobox 1 2.13519
OLFM1 olfactomedin 1 2.08893
NKX2-2 NK2 homeobox 2 2.00414
NSG2 neuronal vesicle trafficking associated 2 2.00246

decreased expression

Symbol Name Standardized Value
PUF60 poly-U binding splicing factor 60KDa -4.8487
C2CD5 C2 calcium-dependent domain containing 5 -4.15349
FASTKD5 FAST kinase domains 5 -2.94746
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.94384
GRWD1 glutamate-rich WD repeat containing 1 -2.47217
PRR16 proline rich 16 -2.15782
GPAA1 glycosylphosphatidylinositol anchor attachment 1 -2.10386