CRCGN017_MCF10A.TP53.M_24H:L17 Gene Set
Genes
42 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:L17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
AGR2
|
anterior gradient 2
|
3.75527
|
|
UBR7
|
ubiquitin protein ligase E3 component n-recognin 7 (putative)
|
3.28186
|
|
WIF1
|
WNT inhibitory factor 1
|
3.14253
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.95946
|
|
STAP2
|
signal transducing adaptor family member 2
|
2.80737
|
|
PSMD2
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
|
2.76899
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
2.64542
|
|
CETN3
|
centrin, EF-hand protein, 3
|
2.58753
|
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
|
2.57946
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.43248
|
|
MMP1
|
matrix metallopeptidase 1
|
2.37852
|
|
HBA1
|
hemoglobin, alpha 1
|
2.2762
|
|
PDLIM1
|
PDZ and LIM domain 1
|
2.26842
|
|
COX6C
|
cytochrome c oxidase subunit VIc
|
2.24238
|
|
SMN2
|
survival of motor neuron 2, centromeric
|
2.188
|
|
PRDX1
|
peroxiredoxin 1
|
2.16357
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
2.12298
|
|
SDHB
|
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
|
2.09047
|
|
IGHMBP2
|
immunoglobulin mu binding protein 2
|
2.08058
|
|
PUF60
|
poly-U binding splicing factor 60KDa
|
2.06196
|
|
DHRS2
|
dehydrogenase/reductase (SDR family) member 2
|
2.02811
|
|
CNRIP1
|
cannabinoid receptor interacting protein 1
|
2.01076
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TIMM9
|
translocase of inner mitochondrial membrane 9 homolog (yeast)
|
-4.87523
|
|
COG2
|
component of oligomeric golgi complex 2
|
-4.78105
|
|
BASP1
|
brain abundant, membrane attached signal protein 1
|
-4.56686
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-4.55501
|
|
LRRC8D
|
leucine rich repeat containing 8 family, member D
|
-2.8761
|
|
ATF5
|
activating transcription factor 5
|
-2.84894
|
|
GDF15
|
growth differentiation factor 15
|
-2.69578
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.31245
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.30653
|
|
ACTR8
|
ARP8 actin-related protein 8 homolog (yeast)
|
-2.28895
|
|
STARD7
|
StAR-related lipid transfer (START) domain containing 7
|
-2.28463
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.22378
|
|
HOXA5
|
homeobox A5
|
-2.21522
|
|
PLEKHA6
|
pleckstrin homology domain containing, family A member 6
|
-2.08467
|
|
POLR3C
|
polymerase (RNA) III (DNA directed) polypeptide C (62kD)
|
-2.06129
|
|
MLST8
|
MTOR associated protein, LST8 homolog (S. cerevisiae)
|
-2.05431
|
|
DENND4B
|
DENN/MADD domain containing 4B
|
-2.03203
|
|
CBX4
|
chromobox homolog 4
|
-2.03056
|
|
ERMAP
|
erythroblast membrane-associated protein (Scianna blood group)
|
-2.01433
|
|
GBE1
|
glucan (1,4-alpha-), branching enzyme 1
|
-2.00413
|
