| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | sulforaphane 32.62 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
55 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:L23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TBX2 | T-box 2 | 6.8066 |
| TXNRD1 | thioredoxin reductase 1 | 6.02989 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | 4.14601 |
| RAB11FIP2 | RAB11 family interacting protein 2 (class I) | 3.61037 |
| SQSTM1 | sequestosome 1 | 3.51941 |
| SKIC2 | SKI2 subunit of superkiller complex | 3.15818 |
| UGDH | UDP-glucose 6-dehydrogenase | 2.96584 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 2.6518 |
| VGLL4 | vestigial-like family member 4 | 2.58285 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 2.56692 |
| HMOX1 | heme oxygenase 1 | 2.47026 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 2.43228 |
| PRKCH | protein kinase C, eta | 2.40171 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 2.39916 |
| GPC1 | glypican 1 | 2.3401 |
| CCNA1 | cyclin A1 | 2.31343 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 2.29226 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 2.27029 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 2.25387 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 | 2.22946 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 | 2.21501 |
| CADM1 | cell adhesion molecule 1 | 2.21445 |
| BYSL | bystin-like | 2.21283 |
| APOE | apolipoprotein E | 2.20958 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.18999 |
| PLSCR3 | phospholipid scramblase 3 | 2.14754 |
| FRS2 | fibroblast growth factor receptor substrate 2 | 2.12638 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 2.10616 |
| EMX2 | empty spiracles homeobox 2 | 2.10077 |
| WASHC5 | WASH complex subunit 5 | 2.07777 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 2.07206 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 2.0499 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 2.04546 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NLRP4 | NLR family, pyrin domain containing 4 | -3.79156 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -3.52222 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -3.1621 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -2.67487 |
| CDK7 | cyclin-dependent kinase 7 | -2.66149 |
| INPP1 | inositol polyphosphate-1-phosphatase | -2.40762 |
| GPM6A | glycoprotein M6A | -2.38406 |
| GRN | granulin | -2.36762 |
| RNF167 | ring finger protein 167 | -2.34632 |
| ZMYM2 | zinc finger, MYM-type 2 | -2.30245 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | -2.28661 |
| KRT14 | keratin 14, type I | -2.26491 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.24409 |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | -2.22114 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -2.21183 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -2.15001 |
| CRYZ | crystallin, zeta (quinone reductase) | -2.11381 |
| SNX6 | sorting nexin 6 | -2.09689 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | -2.08861 |
| PSPC1 | paraspeckle component 1 | -2.06158 |
| MMRN1 | multimerin 1 | -2.02038 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -2.00553 |
