| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | sulforaphane 10.87 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
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65 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:L24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 5.01565 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 4.97332 |
| HYOU1 | hypoxia up-regulated 1 | 4.95755 |
| SSBP2 | single-stranded DNA binding protein 2 | 4.82629 |
| STAP2 | signal transducing adaptor family member 2 | 4.59023 |
| GRB10 | growth factor receptor-bound protein 10 | 3.59148 |
| FGFR4 | fibroblast growth factor receptor 4 | 3.42637 |
| SPAG4 | sperm associated antigen 4 | 3.10885 |
| NOTCH1 | notch 1 | 2.95441 |
| ZNF432 | zinc finger protein 432 | 2.85293 |
| RAP1GAP | RAP1 GTPase activating protein | 2.75517 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 2.65221 |
| WASHC5 | WASH complex subunit 5 | 2.63532 |
| GSTT1 | glutathione S-transferase theta 1 | 2.62855 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 2.57847 |
| TRAPPC4 | trafficking protein particle complex 4 | 2.48169 |
| ANO10 | anoctamin 10 | 2.4226 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 2.31492 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 2.25774 |
| E2F2 | E2F transcription factor 2 | 2.22055 |
| EIF4H | eukaryotic translation initiation factor 4H | 2.21122 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 2.16272 |
| COQ8A | coenzyme Q8A | 2.15085 |
| PLCB4 | phospholipase C, beta 4 | 2.13716 |
| CCT7 | chaperonin containing TCP1, subunit 7 (eta) | 2.11403 |
| KRT18 | keratin 18, type I | 2.10524 |
| AGR2 | anterior gradient 2 | 2.0842 |
| FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) | 2.04473 |
| RBBP5 | retinoblastoma binding protein 5 | 2.04415 |
| GPX3 | glutathione peroxidase 3 | 2.03019 |
| RPS25 | ribosomal protein S25 | 2.02946 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COG2 | component of oligomeric golgi complex 2 | -4.96396 |
| GTPBP8 | GTP-binding protein 8 (putative) | -4.82594 |
| LDHD | lactate dehydrogenase D | -3.33161 |
| KRT14 | keratin 14, type I | -3.07079 |
| SLC25A46 | solute carrier family 25, member 46 | -3.06734 |
| COQ9 | coenzyme Q9 | -3.06329 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -2.78497 |
| CRYZL1 | crystallin, zeta (quinone reductase)-like 1 | -2.76063 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -2.61899 |
| TTC13 | tetratricopeptide repeat domain 13 | -2.55392 |
| PSME3IP1 | proteasome activator subunit 3 interacting protein 1 | -2.54043 |
| UNC119 | unc-119 homolog (C. elegans) | -2.46433 |
| SLC35A1 | solute carrier family 35 (CMP-sialic acid transporter), member A1 | -2.41927 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -2.41505 |
| NIPSNAP2 | nipsnap homolog 2 | -2.4139 |
| HCK | HCK proto-oncogene, Src family tyrosine kinase | -2.347 |
| HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 | -2.32837 |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 | -2.24174 |
| CDC7 | cell division cycle 7 | -2.23946 |
| ANXA1 | annexin A1 | -2.20096 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | -2.1729 |
| TES | testin LIM domain protein | -2.17111 |
| SH2D2A | SH2 domain containing 2A | -2.13771 |
| PLSCR4 | phospholipid scramblase 4 | -2.12295 |
| TCEAL9 | transcription elongation factor A like 9 | -2.11047 |
| CAV2 | caveolin 2 | -2.10108 |
| GALT | galactose-1-phosphate uridylyltransferase | -2.09414 |
| IL11RA | interleukin 11 receptor, alpha | -2.0614 |
| SLC35A5 | solute carrier family 35, member A5 | -2.05784 |
| ZNHIT6 | zinc finger, HIT-type containing 6 | -2.02007 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | -2.01604 |
| MGST3 | microsomal glutathione S-transferase 3 | -2.01452 |
| COG5 | component of oligomeric golgi complex 5 | -2.00473 |
| DUS4L | dihydrouridine synthase 4-like (S. cerevisiae) | -2.0024 |