CRCGN017_MCF10A.TP53.M_24H:M01 Gene Set
Genes
43 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:M01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MYLK
|
myosin light chain kinase
|
5.5203
|
|
SUV39H1
|
suppressor of variegation 3-9 homolog 1 (Drosophila)
|
4.9547
|
|
INTS3
|
integrator complex subunit 3
|
4.56515
|
|
WIF1
|
WNT inhibitory factor 1
|
4.29315
|
|
SH3BP5
|
SH3-domain binding protein 5 (BTK-associated)
|
3.81857
|
|
ABCF1
|
ATP-binding cassette, sub-family F (GCN20), member 1
|
3.0138
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
2.5236
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
2.45645
|
|
ACTG2
|
actin, gamma 2, smooth muscle, enteric
|
2.4377
|
|
PDIA5
|
protein disulfide isomerase family A, member 5
|
2.21705
|
|
MRPS17
|
mitochondrial ribosomal protein S17
|
2.20865
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.20208
|
|
TMOD1
|
tropomodulin 1
|
2.19877
|
|
GATAD2A
|
GATA zinc finger domain containing 2A
|
2.19565
|
|
CHAC1
|
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
|
2.1938
|
|
USP6NL
|
USP6 N-terminal like
|
2.19315
|
|
FPGS
|
folylpolyglutamate synthase
|
2.1635
|
|
PRR7
|
proline rich 7 (synaptic)
|
2.14135
|
|
MUC1
|
mucin 1, cell surface associated
|
2.1023
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
2.074
|
|
CNN1
|
calponin 1, basic, smooth muscle
|
2.05335
|
|
FURIN
|
furin (paired basic amino acid cleaving enzyme)
|
2.048
|
|
ZNF35
|
zinc finger protein 35
|
2.03155
|
|
AKT2
|
v-akt murine thymoma viral oncogene homolog 2
|
2.02147
|
|
TTPAL
|
tocopherol (alpha) transfer protein-like
|
2.00885
|
|
GALK1
|
galactokinase 1
|
2.0053
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HMG20B
|
high mobility group 20B
|
-5.18538
|
|
TSPAN4
|
tetraspanin 4
|
-4.90345
|
|
HAT1
|
histone acetyltransferase 1
|
-4.8186
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.61245
|
|
GDF15
|
growth differentiation factor 15
|
-3.3843
|
|
CRTAP
|
cartilage associated protein
|
-3.3184
|
|
THAP11
|
THAP domain containing 11
|
-2.99685
|
|
TCTA
|
T-cell leukemia translocation altered
|
-2.8484
|
|
IGFBP7
|
insulin-like growth factor binding protein 7
|
-2.48515
|
|
PIK3C2B
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
|
-2.45345
|
|
FBXL4
|
F-box and leucine-rich repeat protein 4
|
-2.37565
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-2.212
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.09775
|
|
LYSET
|
lysosomal enzyme trafficking factor
|
-2.0835
|
|
FSTL1
|
follistatin-like 1
|
-2.056
|
|
XPA
|
xeroderma pigmentosum, complementation group A
|
-2.0236
|
|
MIDEAS
|
mitotic deacetylase associated SANT domain protein
|
-2.0073
|
