CRCGN017_MCF10A.TP53.M_24H:M02 Gene Set
Genes
42 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:M02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CERK
|
ceramide kinase
|
5.1205
|
|
HDGFL3
|
HDGF like 3
|
3.8088
|
|
HYOU1
|
hypoxia up-regulated 1
|
3.58605
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
3.52385
|
|
RBP4
|
retinol binding protein 4, plasma
|
2.99575
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
2.8026
|
|
AIFM1
|
apoptosis-inducing factor, mitochondrion-associated, 1
|
2.6305
|
|
POLR1D
|
polymerase (RNA) I polypeptide D, 16kDa
|
2.52828
|
|
SRBD1
|
S1 RNA binding domain 1
|
2.51815
|
|
NKX2-5
|
NK2 homeobox 5
|
2.47835
|
|
FBXO11
|
F-box protein 11
|
2.46693
|
|
TMEM208
|
transmembrane protein 208
|
2.35385
|
|
HOXD11
|
homeobox D11
|
2.30505
|
|
CENPE
|
centromere protein E, 312kDa
|
2.2471
|
|
EVL
|
Enah/Vasp-like
|
2.158
|
|
NOL8
|
nucleolar protein 8
|
2.12525
|
|
LHX1
|
LIM homeobox 1
|
2.1139
|
|
SORL1
|
sortilin-related receptor, L(DLR class) A repeats containing
|
2.1052
|
|
ALOX12
|
arachidonate 12-lipoxygenase
|
2.0772
|
|
SEC63
|
SEC63 homolog (S. cerevisiae)
|
2.06378
|
|
CAAP1
|
caspase activity and apoptosis inhibitor 1
|
2.03465
|
|
KLK11
|
kallikrein-related peptidase 11
|
2.03415
|
|
TK1
|
thymidine kinase 1, soluble
|
2.0208
|
|
SMAD7
|
SMAD family member 7
|
2.0107
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB1
|
cyclin B1
|
-5.2591
|
|
SCYL3
|
SCY1-like 3 (S. cerevisiae)
|
-5.06225
|
|
VAT1
|
vesicle amine transport 1
|
-4.9836
|
|
AKR7A2
|
aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
|
-4.58397
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.37565
|
|
ARPP19
|
cAMP-regulated phosphoprotein, 19kDa
|
-3.76443
|
|
AKR7A3
|
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
|
-2.95985
|
|
DDB1
|
damage-specific DNA binding protein 1, 127kDa
|
-2.9125
|
|
SAC3D1
|
SAC3 domain containing 1
|
-2.7316
|
|
POLG2
|
polymerase (DNA directed), gamma 2, accessory subunit
|
-2.46813
|
|
GTF2H2C
|
GTF2H2 family member C
|
-2.4276
|
|
FIBP
|
fibroblast growth factor (acidic) intracellular binding protein
|
-2.3093
|
|
AURKC
|
aurora kinase C
|
-2.21785
|
|
TBCA
|
tubulin folding cofactor A
|
-2.18765
|
|
SPIB
|
Spi-B transcription factor (Spi-1/PU.1 related)
|
-2.167
|
|
HCFC1R1
|
host cell factor C1 regulator 1 (XPO1 dependent)
|
-2.10637
|
|
AK6
|
adenylate kinase 6
|
-2.05645
|
|
GCLM
|
glutamate-cysteine ligase, modifier subunit
|
-2.0204
|
