CRCGN017_MCF10A.TP53.M_24H:M03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzofuran 11.42 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

52 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:M03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KCTD5 potassium channel tetramerization domain containing 5 4.98833
PEX11A peroxisomal biogenesis factor 11 alpha 4.27879
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 3.66145
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 3.40377
LGMN legumain 3.01217
RAB27A RAB27A, member RAS oncogene family 2.92073
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.82695
C5 complement component 5 2.78122
HCRT hypocretin (orexin) neuropeptide precursor 2.4773
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 2.45686
HLA-DMA major histocompatibility complex, class II, DM alpha 2.43293
CAVIN2 caveolae associated protein 2 2.40899
OSMR oncostatin M receptor 2.32762
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 2.2988
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 2.29097
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain 2.27747
MLXIP MLX interacting protein 2.1831
TLE2 transducin-like enhancer of split 2 2.13049
ZNF460 zinc finger protein 460 2.12215
STEAP4 STEAP family member 4 2.10752
CCDC82 coiled-coil domain containing 82 2.09539
PDE8B phosphodiesterase 8B 2.0897
STAT5B signal transducer and activator of transcription 5B 2.07168
ATAD2B ATPase family, AAA domain containing 2B 2.07064
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 2.05526
TPO thyroid peroxidase 2.04853
BLTP1 bridge-like lipid transfer protein family member 1 2.04619
ELOVL2 ELOVL fatty acid elongase 2 2.03478
EPN2 epsin 2 2.03395
ZNF510 zinc finger protein 510 2.01967
ZNF480 zinc finger protein 480 2.01543
ZNF37A zinc finger protein 37A 2.00319

decreased expression

Symbol Name Standardized Value
PUF60 poly-U binding splicing factor 60KDa -5.05236
ARPP19 cAMP-regulated phosphoprotein, 19kDa -4.42661
TUBA4A tubulin, alpha 4a -3.37729
CD81 CD81 molecule -3.37239
HMG20B high mobility group 20B -3.33695
KRT14 keratin 14, type I -3.29547
DIPK1A divergent protein kinase domain 1A -2.63203
SCRIB scribbled planar cell polarity protein -2.62932
CDK4 cyclin-dependent kinase 4 -2.62508
GRN granulin -2.5021
SDC1 syndecan 1 -2.44254
BASP1 brain abundant, membrane attached signal protein 1 -2.42198
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) -2.28332
STYXL1 serine/threonine/tyrosine interacting-like 1 -2.22971
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -2.192
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) -2.17551
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.09999
SIGLEC15 sialic acid binding Ig-like lectin 15 -2.09215
PMVK phosphomevalonate kinase -2.03632
DDN dendrin -2.00301