CRCGN017_MCF10A.TP53.M_24H:M05 Gene Set
Genes
52 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:M05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
6.38984
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.76661
|
|
RBP4
|
retinol binding protein 4, plasma
|
4.77172
|
|
LAGE3
|
L antigen family, member 3
|
4.70279
|
|
BMP4
|
bone morphogenetic protein 4
|
3.42581
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
3.07213
|
|
FAM3A
|
family with sequence similarity 3, member A
|
2.72892
|
|
FAM50A
|
family with sequence similarity 50, member A
|
2.56094
|
|
DKC1
|
dyskeratosis congenita 1, dyskerin
|
2.49536
|
|
ENG
|
endoglin
|
2.46862
|
|
NAT10
|
N-acetyltransferase 10 (GCN5-related)
|
2.46079
|
|
DPH2
|
DPH2 homolog (S. cerevisiae)
|
2.44585
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
2.43651
|
|
TBX2
|
T-box 2
|
2.35258
|
|
TLCD3A
|
TLC domain containing 3A
|
2.33636
|
|
SLC10A3
|
solute carrier family 10, member 3
|
2.24922
|
|
AKAP8
|
A kinase (PRKA) anchor protein 8
|
2.1762
|
|
ROBO4
|
roundabout, axon guidance receptor, homolog 4 (Drosophila)
|
2.14939
|
|
SNRPG
|
small nuclear ribonucleoprotein polypeptide G
|
2.09836
|
|
CBFB
|
core-binding factor, beta subunit
|
2.09485
|
|
MBNL2
|
muscleblind-like splicing regulator 2
|
2.08101
|
|
KRT20
|
keratin 20, type I
|
2.07017
|
|
DCBLD2
|
discoidin, CUB and LCCL domain containing 2
|
2.06651
|
|
BCAP31
|
B-cell receptor-associated protein 31
|
2.06165
|
|
APTX
|
aprataxin
|
2.05228
|
|
CYTL1
|
cytokine-like 1
|
2.04868
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-4.8674
|
|
TUBA4A
|
tubulin, alpha 4a
|
-4.57139
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-4.3873
|
|
KRT14
|
keratin 14, type I
|
-3.76593
|
|
BASP1
|
brain abundant, membrane attached signal protein 1
|
-3.51571
|
|
CD58
|
CD58 molecule
|
-3.33168
|
|
PIH1D1
|
PIH1 domain containing 1
|
-3.12744
|
|
GRN
|
granulin
|
-3.11493
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.63195
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.42105
|
|
MMP7
|
matrix metallopeptidase 7
|
-2.28703
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.28151
|
|
SCPEP1
|
serine carboxypeptidase 1
|
-2.27784
|
|
PSENEN
|
presenilin enhancer gamma secretase subunit
|
-2.27454
|
|
NME5
|
NME/NM23 family member 5
|
-2.26915
|
|
NCF1
|
neutrophil cytosolic factor 1
|
-2.22559
|
|
FGR
|
FGR proto-oncogene, Src family tyrosine kinase
|
-2.15185
|
|
NUPR1
|
nuclear protein, transcriptional regulator, 1
|
-2.13777
|
|
CSTA
|
cystatin A (stefin A)
|
-2.12876
|
|
STBD1
|
starch binding domain 1
|
-2.11667
|
|
PIK3C2B
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
|
-2.1036
|
|
SHOX
|
short stature homeobox
|
-2.08778
|
|
LARP6
|
La ribonucleoprotein domain family, member 6
|
-2.05445
|
|
SDHAF1
|
succinate dehydrogenase complex assembly factor 1
|
-2.05206
|
|
LIN37
|
lin-37 DREAM MuvB core complex component
|
-2.04543
|
|
EHHADH
|
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
|
-2.02416
|
