| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2,4-diaminoanisole sulfate 11.37 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
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162 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:M06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 5.45186 |
| TBPL1 | TBP-like 1 | 5.26793 |
| COMP | cartilage oligomeric matrix protein | 5.0 |
| HBA1 | hemoglobin, alpha 1 | 4.91089 |
| NUP153 | nucleoporin 153kDa | 3.8119 |
| TBX2 | T-box 2 | 3.51515 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 3.46639 |
| RBP4 | retinol binding protein 4, plasma | 3.38525 |
| HBB | hemoglobin, beta | 3.25733 |
| RNF111 | ring finger protein 111 | 3.24179 |
| CDCA4 | cell division cycle associated 4 | 3.16733 |
| THOC1 | THO complex 1 | 2.9903 |
| COXFA4L2 | cytochrome c oxidase hypoxia associated subunit FA4L2 | 2.97122 |
| WDR91 | WD repeat domain 91 | 2.96569 |
| BPGM | 2,3-bisphosphoglycerate mutase | 2.92197 |
| NUP205 | nucleoporin 205kDa | 2.85668 |
| CYREN | cell cycle regulator of NHEJ | 2.74209 |
| VWA1 | von Willebrand factor A domain containing 1 | 2.63848 |
| MFSD1 | major facilitator superfamily domain containing 1 | 2.6335 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 2.57802 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine | 2.54204 |
| ZNF107 | zinc finger protein 107 | 2.50756 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | 2.49702 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 2.46182 |
| ZNF175 | zinc finger protein 175 | 2.41845 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 2.40822 |
| NRXN2 | neurexin 2 | 2.40544 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | 2.38659 |
| MGP | matrix Gla protein | 2.37515 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 2.36732 |
| ADAMTSL4 | ADAMTS-like 4 | 2.36537 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 | 2.35369 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 2.34953 |
| EIF4ENIF1 | eukaryotic translation initiation factor 4E nuclear import factor 1 | 2.34817 |
| SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | 2.33215 |
| IL7 | interleukin 7 | 2.32198 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 2.30687 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 2.30454 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) | 2.29934 |
| BARD1 | BRCA1 associated RING domain 1 | 2.28887 |
| VLDLR | very low density lipoprotein receptor | 2.27201 |
| LRRC61 | leucine rich repeat containing 61 | 2.26115 |
| GPATCH1 | G patch domain containing 1 | 2.25133 |
| CHRFAM7A | CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion | 2.22616 |
| NYNRIN | NYN domain and retroviral integrase containing | 2.21939 |
| GOSR1 | golgi SNAP receptor complex member 1 | 2.20128 |
| EFHD1 | EF-hand domain family, member D1 | 2.20005 |
| NRG2 | neuregulin 2 | 2.17515 |
| ZMYM6 | zinc finger, MYM-type 6 | 2.16719 |
| CCDC102B | coiled-coil domain containing 102B | 2.13632 |
| KRT19 | keratin 19, type I | 2.13524 |
| VPS52 | vacuolar protein sorting 52 homolog (S. cerevisiae) | 2.13088 |
| EBAG9 | estrogen receptor binding site associated, antigen, 9 | 2.13027 |
| ASCC2 | activating signal cointegrator 1 complex subunit 2 | 2.12319 |
| SOD3 | superoxide dismutase 3, extracellular | 2.11818 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 2.11814 |
| MAB21L4 | mab-21 like 4 | 2.11587 |
| FAM184A | family with sequence similarity 184, member A | 2.11358 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 2.11302 |
| GDF7 | growth differentiation factor 7 | 2.11271 |
| NPC1L1 | NPC1-like 1 | 2.11257 |
| CFI | complement factor I | 2.11078 |
| ZNF512B | zinc finger protein 512B | 2.10586 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 2.10129 |
| CPNE2 | copine II | 2.09508 |
| ZNF232 | zinc finger protein 232 | 2.08374 |
| ZNF34 | zinc finger protein 34 | 2.08362 |
| MAPT | microtubule-associated protein tau | 2.0831 |
| CA9 | carbonic anhydrase IX | 2.07942 |
| TLR4 | toll-like receptor 4 | 2.07901 |
| WDR45B | WD repeat domain 45B | 2.07593 |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) | 2.07511 |
| HIRIP3 | HIRA interacting protein 3 | 2.06678 |
| MYT1L | myelin transcription factor 1-like | 2.06406 |
| FABP6 | fatty acid binding protein 6, ileal | 2.06094 |
| HILPDA | hypoxia inducible lipid droplet-associated | 2.05944 |
| SLC35F6 | solute carrier family 35, member F6 | 2.05817 |
| CD200 | CD200 molecule | 2.04929 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 2.04351 |
| SCRG1 | stimulator of chondrogenesis 1 | 2.04248 |
| MBNL3 | muscleblind-like splicing regulator 3 | 2.03605 |
| NPTN | neuroplastin | 2.02738 |
| TRIM26 | tripartite motif containing 26 | 2.01235 |
| DUSP9 | dual specificity phosphatase 9 | 2.00852 |
| SCAF8 | SR-related CTD-associated factor 8 | 2.00558 |
| SERPINB10 | serpin peptidase inhibitor, clade B (ovalbumin), member 10 | 2.00403 |
| LGMN | legumain | 2.00291 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HMG20B | high mobility group 20B | -6.71667 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -6.16132 |
| ACOT9 | acyl-CoA thioesterase 9 | -5.76511 |
| HAT1 | histone acetyltransferase 1 | -5.52667 |
| CDC25B | cell division cycle 25B | -4.92517 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -4.9022 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.62805 |
| MSN | moesin | -4.44625 |
| PRDX4 | peroxiredoxin 4 | -3.71208 |
| CRTAP | cartilage associated protein | -3.48296 |
| PAEP | progestagen-associated endometrial protein | -3.47968 |
| REEP5 | receptor accessory protein 5 | -3.19789 |
| LOC127933115 | uncharacterized LOC127933115 | -3.19163 |
| LDHD | lactate dehydrogenase D | -3.15216 |
| MRPS16 | mitochondrial ribosomal protein S16 | -2.98157 |
| EMC6 | ER membrane protein complex subunit 6 | -2.94175 |
| LAMTOR2 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 | -2.86048 |
| ATF5 | activating transcription factor 5 | -2.85826 |
| CD320 | CD320 molecule | -2.83187 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | -2.71479 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | -2.62212 |
| RAB9A | RAB9A, member RAS oncogene family | -2.61756 |
| APOO | apolipoprotein O | -2.60261 |
| PFKM | phosphofructokinase, muscle | -2.53983 |
| FSTL1 | follistatin-like 1 | -2.53332 |
| LSM8 | LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.50526 |
| RPL10A | ribosomal protein L10a | -2.49701 |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) | -2.45748 |
| MTMR11 | myotubularin related protein 11 | -2.45134 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | -2.4417 |
| MRM3 | mitochondrial rRNA methyltransferase 3 | -2.43565 |
| MAP3K3 | mitogen-activated protein kinase kinase kinase 3 | -2.43128 |
| CUEDC2 | CUE domain containing 2 | -2.41449 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -2.40671 |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X | -2.40312 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | -2.39508 |
| DHTKD1 | dehydrogenase E1 and transketolase domain containing 1 | -2.38036 |
| RPL18A | ribosomal protein L18a | -2.31381 |
| ECI2 | enoyl-CoA delta isomerase 2 | -2.29425 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | -2.29329 |
| TSTD1 | thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 | -2.26172 |
| KRT14 | keratin 14, type I | -2.25678 |
| SSNA1 | Sjogren syndrome nuclear autoantigen 1 | -2.24734 |
| DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3 | -2.23468 |
| ZBED1 | zinc finger, BED-type containing 1 | -2.21764 |
| ASMTL | acetylserotonin O-methyltransferase-like | -2.20052 |
| NDUFS7 | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | -2.19518 |
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 | -2.19427 |
| PPP1R26 | protein phosphatase 1, regulatory subunit 26 | -2.19051 |
| POLR2J3 | polymerase (RNA) II (DNA directed) polypeptide J3 | -2.18562 |
| CLPP | caseinolytic mitochondrial matrix peptidase proteolytic subunit | -2.18479 |
| GIMAP4 | GTPase, IMAP family member 4 | -2.18466 |
| MMP3 | matrix metallopeptidase 3 | -2.18123 |
| NXN | nucleoredoxin | -2.17546 |
| PSMD6 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | -2.16051 |
| RPL29 | ribosomal protein L29 | -2.15862 |
| LYSET | lysosomal enzyme trafficking factor | -2.15601 |
| TMEM187 | transmembrane protein 187 | -2.15242 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.1454 |
| HNRNPH2 | heterogeneous nuclear ribonucleoprotein H2 (H') | -2.12543 |
| CDC42SE1 | CDC42 small effector 1 | -2.12434 |
| BORCS6 | BLOC-1 related complex subunit 6 | -2.122 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -2.10623 |
| EVI2A | ecotropic viral integration site 2A | -2.10252 |
| SSR4 | signal sequence receptor, delta | -2.09416 |
| MEPCE | methylphosphate capping enzyme | -2.07894 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated | -2.07364 |
| RPL36A | ribosomal protein L36a | -2.06942 |
| DCTN6 | dynactin 6 | -2.05955 |
| AVPI1 | arginine vasopressin-induced 1 | -2.05786 |
| GATD3 | glutamine amidotransferase class 1 domain containing 3 | -2.03223 |
| SNPH | syntaphilin | -2.02999 |
| ZFHX4 | zinc finger homeobox 4 | -2.02476 |
| RHOC | ras homolog family member C | -2.00533 |
| PMPCA | peptidase (mitochondrial processing) alpha | -2.00239 |