CRCGN017_MCF10A.TP53.M_24H:M08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description chlordane 33.27 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:M08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TOMM34 translocase of outer mitochondrial membrane 34 4.96654
ADGRE5 adhesion G protein-coupled receptor E5 3.05624
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.48636
IGHMBP2 immunoglobulin mu binding protein 2 2.41459
TPGS1 tubulin polyglutamylase complex subunit 1 2.18853
TBPL1 TBP-like 1 2.17815
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 2.16355
SPAG4 sperm associated antigen 4 2.11927

decreased expression

Symbol Name Standardized Value
CTNND1 catenin (cadherin-associated protein), delta 1 -3.73468
CCNB1 cyclin B1 -3.56504
SLC25A46 solute carrier family 25, member 46 -3.51953
TUBB6 tubulin, beta 6 class V -3.40814
RPA3 replication protein A3, 14kDa -3.08879
NRIP1 nuclear receptor interacting protein 1 -2.82719
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -2.61851
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.49213
ZMYM2 zinc finger, MYM-type 2 -2.42777
SPAG7 sperm associated antigen 7 -2.30154
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.20796
MSMO1 methylsterol monooxygenase 1 -2.14008
TNIP1 TNFAIP3 interacting protein 1 -2.00207