CRCGN017_MCF10A.TP53.M_24H:M09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description chlordane 11.09 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:M09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
INTS3 integrator complex subunit 3 4.86514
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 4.83865
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 4.63133
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 3.46222
TRIB3 tribbles pseudokinase 3 2.68824
PDLIM1 PDZ and LIM domain 1 2.39277
TCTN1 tectonic family member 1 2.04748

decreased expression

Symbol Name Standardized Value
BASP1 brain abundant, membrane attached signal protein 1 -4.96962
TUBB6 tubulin, beta 6 class V -4.7825
CANT1 calcium activated nucleotidase 1 -4.77328
PCNA proliferating cell nuclear antigen -4.5643
ADI1 acireductone dioxygenase 1 -4.53116
NT5DC2 5'-nucleotidase domain containing 2 -4.05732
GDF15 growth differentiation factor 15 -3.62152
CDK4 cyclin-dependent kinase 4 -3.42686
NUSAP1 nucleolar and spindle associated protein 1 -3.15477
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.11917
CORO1A coronin, actin binding protein, 1A -2.86904
ANXA2 annexin A2 -2.41649
PPIC peptidylprolyl isomerase C (cyclophilin C) -2.30171
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.02847