CRCGN017_MCF10A.TP53.M_24H:M10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description styrene 98.8 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

46 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:M10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SNAP25 synaptosomal-associated protein, 25kDa 5.26149
GFOD1 glucose-fructose oxidoreductase domain containing 1 3.48019
CNPY3 canopy FGF signaling regulator 3 3.07716
STMN2 stathmin 2 2.96301
PPT2 palmitoyl-protein thioesterase 2 2.77258
NSG2 neuronal vesicle trafficking associated 2 2.74413
MYL9 myosin, light chain 9, regulatory 2.47903
CHN1 chimerin 1 2.34863
INA internexin neuronal intermediate filament protein, alpha 2.34232
SCGN secretagogin, EF-hand calcium binding protein 2.30945
SYN1 synapsin I 2.29885
PRSS23 protease, serine, 23 2.25018
ELAVL4 ELAV like neuron-specific RNA binding protein 4 2.2291
NEFL neurofilament, light polypeptide 2.21869
CHGB chromogranin B 2.20114
SYT1 synaptotagmin I 2.20009
SNAP91 synaptosomal-associated protein, 91kDa 2.13346
BEX2 brain expressed X-linked 2 2.13134
NEFM neurofilament, medium polypeptide 2.11472
TPGS1 tubulin polyglutamylase complex subunit 1 2.05187
OLFM1 olfactomedin 1 2.04902

decreased expression

Symbol Name Standardized Value
WASHC4 WASH complex subunit 4 -6.12539
KRT14 keratin 14, type I -4.88668
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -4.18497
HMG20B high mobility group 20B -4.16267
MSN moesin -3.99222
CD81 CD81 molecule -3.41366
PIH1D1 PIH1 domain containing 1 -3.14797
OSBPL8 oxysterol binding protein-like 8 -3.0999
ARPP19 cAMP-regulated phosphoprotein, 19kDa -2.89023
RBM34 RNA binding motif protein 34 -2.79891
GDF15 growth differentiation factor 15 -2.59567
NPDC1 neural proliferation, differentiation and control, 1 -2.51272
PDZK1IP1 PDZK1 interacting protein 1 -2.51238
CD9 CD9 molecule -2.44025
GPATCH1 G patch domain containing 1 -2.36488
ACTR6 ARP6 actin-related protein 6 homolog (yeast) -2.33408
RPA3 replication protein A3, 14kDa -2.22845
PSENEN presenilin enhancer gamma secretase subunit -2.22156
TBCB tubulin folding cofactor B -2.21105
ZNF146 zinc finger protein 146 -2.1493
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -2.0402
H1-0 H1.0 linker histone -2.037
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.03557
FAIM Fas apoptotic inhibitory molecule -2.0132
CEP83 centrosomal protein 83kDa -2.00635