CRCGN017_MCF10A.TP53.M_24H:M12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description styrene 10.98 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

18 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:M12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KIF5C kinesin family member 5C 4.66877
ADGRE5 adhesion G protein-coupled receptor E5 4.65742
CNRIP1 cannabinoid receptor interacting protein 1 3.77924
TOMM34 translocase of outer mitochondrial membrane 34 3.46508
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.86192
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 2.78278
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.72733
PRKX protein kinase, X-linked 2.30651
SYNGAP1 synaptic Ras GTPase activating protein 1 2.21271

decreased expression

Symbol Name Standardized Value
TSPAN4 tetraspanin 4 -4.84365
BASP1 brain abundant, membrane attached signal protein 1 -4.80716
HMG20B high mobility group 20B -4.213
CD320 CD320 molecule -3.56261
DCK deoxycytidine kinase -3.1502
GDF15 growth differentiation factor 15 -3.1122
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.98452
CD81 CD81 molecule -2.50626
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.15617