CRCGN017_MCF10A.TP53.M_24H:M16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzo[c]phenanthrene 102.22 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:M16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KCTD5 potassium channel tetramerization domain containing 5 3.79155
LRP10 low density lipoprotein receptor-related protein 10 3.30835
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 3.28198
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 3.15045
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 2.86885
ASCC2 activating signal cointegrator 1 complex subunit 2 2.2582
ZNF451 zinc finger protein 451 2.16395
HMOX1 heme oxygenase 1 2.1262
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.03935

decreased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I -4.55315
RALGDS ral guanine nucleotide dissociation stimulator -4.53127
TUBA4A tubulin, alpha 4a -3.66215
BASP1 brain abundant, membrane attached signal protein 1 -3.52185
CANT1 calcium activated nucleotidase 1 -3.01915
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.95305
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.72725
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.651
REXO2 RNA exonuclease 2 -2.47406
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.09625