CRCGN017_MCF10A.TP53.M_24H:M17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzo[c]phenanthrene 34.07 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:M17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STAP2 signal transducing adaptor family member 2 4.14432
VAV3 vav 3 guanine nucleotide exchange factor 3.67166
AGR2 anterior gradient 2 2.90454
LGMN legumain 2.87676
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 2.87668
CGRRF1 cell growth regulator with ring finger domain 1 2.81589
RBP4 retinol binding protein 4, plasma 2.69389
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2.17347
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.08591
RXYLT1 ribitol xylosyltransferase 1 2.07479
IQGAP2 IQ motif containing GTPase activating protein 2 2.01365

decreased expression

Symbol Name Standardized Value
TLK2 tousled-like kinase 2 -3.63351
HMG20B high mobility group 20B -2.71172
GRWD1 glutamate-rich WD repeat containing 1 -2.65794
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.17149
STRADA STE20-related kinase adaptor alpha -2.02485