CRCGN017_MCF10A.TP53.M_24H:M18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzo[c]phenanthrene 11.36 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

47 genes differentially expressed following the CRCGN017_MCF10A.TP53.M_24H:M18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STIMATE STIM activating enhancer 4.13008
ABHD6 abhydrolase domain containing 6 3.8909
TLR4 toll-like receptor 4 3.7512
PEX11A peroxisomal biogenesis factor 11 alpha 3.25833
MAMLD1 mastermind-like domain containing 1 3.18755
EPHA5 EPH receptor A5 2.29537
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.28435
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 2.23217
GPR39 G protein-coupled receptor 39 2.22074
SPATA17 spermatogenesis associated 17 2.1482
ZNF37A zinc finger protein 37A 2.13989
HSPA1L heat shock 70kDa protein 1-like 2.13854
IL4 interleukin 4 2.13639
AGBL3 ATP/GTP binding protein-like 3 2.13221
CFAP43 cilia and flagella associated protein 43 2.12098
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20 2.11133
ART3 ADP-ribosyltransferase 3 2.10766
AFAP1 actin filament associated protein 1 2.10096
TRPC5 transient receptor potential cation channel, subfamily C, member 5 2.09856
ADGB androglobin 2.09821
GFRA1 GDNF family receptor alpha 1 2.08869
ZNF132 zinc finger protein 132 2.07134
PPIAL4H peptidylprolyl isomerase A like 4H 2.06056
CCDC198 coiled-coil domain containing 198 2.05998
PURG purine-rich element binding protein G 2.04042
STX11 syntaxin 11 2.03615
MLNR motilin receptor 2.03258
TLL1 tolloid-like 1 2.03219
THNSL1 threonine synthase-like 1 (S. cerevisiae) 2.03178
GTPBP10 GTP-binding protein 10 (putative) 2.02723
SLC38A4 solute carrier family 38, member 4 2.02461
GP5 glycoprotein V (platelet) 2.02454
IFNA8 interferon, alpha 8 2.02318
ZNF81 zinc finger protein 81 2.02214
DCC DCC netrin 1 receptor 2.01717
IMPG1 interphotoreceptor matrix proteoglycan 1 2.01396
ZNF157 zinc finger protein 157 2.01132
SOX30 SRY (sex determining region Y)-box 30 2.00261

decreased expression

Symbol Name Standardized Value
ENOPH1 enolase-phosphatase 1 -3.34197
TEX10 testis expressed 10 -3.22192
FPGS folylpolyglutamate synthase -3.18647
GDF15 growth differentiation factor 15 -3.14461
CRK v-crk avian sarcoma virus CT10 oncogene homolog -3.07365
NPDC1 neural proliferation, differentiation and control, 1 -2.89467
GRN granulin -2.8817
DSG2 desmoglein 2 -2.33357
NUSAP1 nucleolar and spindle associated protein 1 -2.01488